Reactome | EPO:EPOR:JAK2:LYN:IRS2 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9006324] protein tyrosine kinase activity of EPO:EPOR:JAK2:LYN:IRS2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-9006332] JAK2 transphosphorylates and is activated in response to Erythropoietin - Homo sapiens
created	[InstanceEdit:9006309] May, Bruce, 2017-05-13
dbId	9006300
displayName	EPO:EPOR:JAK2:LYN:IRS2 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-379001] EPO [extracellular region] [Complex:R-HSA-9006298] EPOR:JAK2:LYN:IRS2 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
isChimeric	false
maxDepth	3
modified	[InstanceEdit:9027265] May, Bruce, 2017-10-29
name	EPO:EPOR:JAK2:LYN:IRS2
producedByEvent	[Reaction:R-HSA-9006325] EPO binds EPOR:JAK2:LYN:IRS2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9006300

(output)	[Reaction:R-HSA-9006325] EPO binds EPOR:JAK2:LYN:IRS2
(input)	[Reaction:R-HSA-9006332] JAK2 transphosphorylates and is activated in response to Erythropoietin
(physicalEntity)	[CatalystActivity:9006324] protein tyrosine kinase activity of EPO:EPOR:JAK2:LYN:IRS2 [plasma membrane]

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