Reactome | IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane]

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IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8985893] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8985929] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B - Homo sapiens
created	[InstanceEdit:8985906] Duenas, Corina, 2017-04-21
dbId	8985997
displayName	IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane]
hasComponent	[Complex:R-HSA-8985933] IL2RG:p-Y904,939-JAK3 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-447260] IL9 [extracellular region] [Complex:R-HSA-8985918] p-Y407-IL9R:JAK1 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] - Mus musculus [Complex:R-RNO-8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] - Canis familiaris [Complex:R-BTA-8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] - Bos taurus [Complex:R-SSC-8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] - Sus scrofa [Complex:R-GGA-8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:8985924] Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity [LiteratureReference:8985894] A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9
maxDepth	3
modified	[InstanceEdit:9822872] D'Eustachio, Peter, 2022-12-29
name	IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3
producedByEvent	[BlackBoxEvent:R-HSA-8985973] IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 - Homo sapiens [BlackBoxEvent:R-HSA-8985900] p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8985997
updateTrackers	[UpdateTracker:9905085] Update Tracker - [Complex:8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] - v84:[modifyName, updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9905085] Update Tracker - [Complex:8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] - v84:[modifyName, updateContainedComponent]
(output)	[BlackBoxEvent:R-HSA-8985973] IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [BlackBoxEvent:R-HSA-8985900] p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3
(input)	[Reaction:R-HSA-8985929] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B
(hasComponent)	[Complex:R-HSA-8985893] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] [Complex:R-HSA-8985982] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane]

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