Reactome | HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:MYBL2 gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8964560] Orlic-Milacic, Marija, 2017-02-17
dbId	8964563
displayName	HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:MYBL2 gene [nucleoplasm]
hasComponent	[DefinedSet:R-HSA-8964549] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8869524] MYBL2 gene [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:1362298] E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
maxDepth	6
name	HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:MYBL2 gene
negativelyRegulates	[NegativeGeneExpressionRegulation:R-HSA-8978928] Negative gene expression regulation by 'HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:MYBL2 gene [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-8964561] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds MYBL2 gene promoter - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8964563

(output)	[Reaction:R-HSA-8964561] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds MYBL2 gene promoter
(regulator)	[NegativeGeneExpressionRegulation:R-HSA-8978928] Negative gene expression regulation by 'HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:MYBL2 gene [nucleoplasm]'

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