Reactome | E2F1:TFDP1,TFDP2:TK1 gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8961990] Orlic-Milacic, Marija, 2017-02-06
dbId	8961992
displayName	E2F1:TFDP1,TFDP2:TK1 gene [nucleoplasm]
hasComponent	[Complex:R-HSA-68653] E2F1:TFDP1,TFDP2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8954007] TK1 gene [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:141354] Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes [LiteratureReference:8961994] G1/S-regulated E2F-containing protein complexes bind to the mouse thymidine kinase gene promoter [LiteratureReference:8961637] Combinatorial gene control involving E2F and E Box family members
maxDepth	4
name	E2F1:TFDP1,TFDP2:TK1 gene
positivelyRegulates	[PositiveGeneExpressionRegulation:R-HSA-8962037] Positive gene expression regulation by 'E2F1:TFDP1,TFDP2:TK1 gene [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-8961991] E2F1 binds the TK1 gene promoter - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8961992

(regulator)	[PositiveGeneExpressionRegulation:R-HSA-8962037] Positive gene expression regulation by 'E2F1:TFDP1,TFDP2:TK1 gene [nucleoplasm]'
(output)	[Reaction:R-HSA-8961991] E2F1 binds the TK1 gene promoter

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