Reactome | CTNNB1:TCF7L2,LEF1 [nucleoplasm]

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CTNNB1:TCF7L2,LEF1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-8853944] CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8951442] CTNNB1:TCF7L2,LEF1 binds the CCND1 gene promoter - Homo sapiens
created	[InstanceEdit:8951441] Orlic-Milacic, Marija, 2016-12-02
dbId	8951439
displayName	CTNNB1:TCF7L2,LEF1 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-3451168] CTNNB1 [nucleoplasm] [DefinedSet:R-HSA-8853943] TCF7L2,LEF1 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Mus musculus [Complex:R-RNO-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Canis familiaris [Complex:R-BTA-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Bos taurus [Complex:R-SSC-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Sus scrofa [Complex:R-DRE-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Danio rerio [Complex:R-XTR-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Gallus gallus [Complex:R-DME-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-4411397] TCF/LEF:CTNNB1 [nucleoplasm] - Caenorhabditis elegans
isChimeric	false
literatureReference	[LiteratureReference:8853951] The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway [LiteratureReference:8853942] Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
maxDepth	3
modified	[InstanceEdit:8951525] Orlic-Milacic, Marija, 2016-12-07
name	CTNNB1:TCF7L2,LEF1 CTNNB1:TCF4,LEF1
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8951439

Referrals

(activeUnit)	[PositiveGeneExpressionRegulation:R-HSA-8951440] Positive gene expression regulation by 'CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:8853948] Positive gene expression regulation by 'CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm]'
(input)	[Reaction:R-HSA-8951442] CTNNB1:TCF7L2,LEF1 binds the CCND1 gene promoter
(hasComponent)	[Complex:R-HSA-8853944] CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm]

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