Reactome | IL12A:EBI3 [endoplasmic reticulum lumen]

Schema > Complex > Entries

compartment	[Compartment:17957] endoplasmic reticulum lumen
consumedByEvent	[BlackBoxEvent:R-HSA-448627] Interleukin-35 translocates from the ER lumen to the extracellular region - Homo sapiens
created	[InstanceEdit:8950688] Duenas, Corina, 2016-12-02
dbId	8950589
displayName	IL12A:EBI3 [endoplasmic reticulum lumen]
hasComponent	[EntityWithAccessionedSequence:R-HSA-8950622] EBI3 [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:R-HSA-8950139] IL12A [endoplasmic reticulum lumen]
inDisease	false
inferredTo	[Complex:R-MMU-8950589] IL12A:EBI3 [endoplasmic reticulum lumen] - Mus musculus [Complex:R-RNO-8950589] IL12A:EBI3 [endoplasmic reticulum lumen] - Rattus norvegicus [Complex:R-CFA-8950589] IL12A:EBI3 [endoplasmic reticulum lumen] - Canis familiaris [Complex:R-BTA-8950589] IL12A:EBI3 [endoplasmic reticulum lumen] - Bos taurus [Complex:R-SSC-8950589] IL12A:EBI3 [endoplasmic reticulum lumen] - Sus scrofa
isChimeric	false
literatureReference	[LiteratureReference:6809130] The inhibitory cytokine IL-35 contributes to regulatory T-cell function
maxDepth	2
name	IL12A:EBI3 IL35 Interleukin-35
producedByEvent	[BlackBoxEvent:R-HSA-8950740] CANX dissociates from IL12A:EBI3 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8950589
summation	[Summation:8950621] Interleukin-35 is a heterodimer of Interleukin-27 subunit be...

(output)	[BlackBoxEvent:R-HSA-8950740] CANX dissociates from IL12A:EBI3
(input)	[BlackBoxEvent:R-HSA-448627] Interleukin-35 translocates from the ER lumen to the extracellular region