Reactome | Association of procollagen type IV

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Association of procollagen type IV Show undefined attributes

authored	[InstanceEdit:2192896] Jupe, S, 2012-04-11
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:8944228] Jupe, Steve, 2016-11-03
dbId	8944265
displayName	Association of procollagen type IV
edited	[InstanceEdit:8944470] Jupe, Steve, 2016-11-03
eventOf	[Pathway:R-HSA-8948216] Collagen chain trimerization - Homo sapiens
followingEvent	[Reaction:R-HSA-2022073] Procollagen triple helix formation - Homo sapiens
input	2 × [DefinedSet:R-HSA-2025676] Alpha-1(IV) chains [endoplasmic reticulum lumen] [DefinedSet:R-HSA-2025671] Alpha-2(IV) chains [endoplasmic reticulum lumen] [DefinedSet:R-HSA-2025668] Alpha-3(IV) chains [endoplasmic reticulum lumen] [DefinedSet:R-HSA-2025678] Alpha-4(IV) chains [endoplasmic reticulum lumen] 3 × [DefinedSet:R-HSA-2025681] Alpha-5(IV) chains [endoplasmic reticulum lumen] [DefinedSet:R-HSA-2025666] Alpha-6(IV) chains [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2008097] Interchain disulfide bonds in procollagen are located in a large nontriple-helical COOH-terminal domain [LiteratureReference:2008075] The role of cis-trans isomerization of peptide bonds in the coil leads to and comes from triple helix conversion of collagen
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Association of procollagen type IV
output	[DefinedSet:R-HSA-2025771] C-linked procollagen type IV trimers [endoplasmic reticulum lumen]
precedingEvent	[BlackBoxEvent:R-HSA-8948231] COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates - Homo sapiens [BlackBoxEvent:R-HSA-8948232] Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases - Homo sapiens [BlackBoxEvent:R-HSA-8948234] P4HB:4-Hyp collagen propeptides dissociates - Homo sapiens [BlackBoxEvent:R-HSA-8948222] PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates - Homo sapiens [BlackBoxEvent:R-HSA-8948224] PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates - Homo sapiens [BlackBoxEvent:R-HSA-8948226] Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates - Homo sapiens
releaseDate	2016-12-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2267224] Canty-Laird, EG, 2012-05-24
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8944265
summation	[Summation:8944213] The C-terminal propeptide is essential for the association o...

Referrals

(hasEvent)	[Pathway:R-HSA-8948216] Collagen chain trimerization
(precedingEvent)	[Reaction:R-HSA-2022073] Procollagen triple helix formation