Reactome | GPLD1 hydrolyses GPI-anchors from proteins

Schema > Reaction > Entries

GPLD1 hydrolyses GPI-anchors from proteins Show undefined attributes

authored	[InstanceEdit:8940389] Jassal, Bijay, 2016-09-26
catalystActivity	[CatalystActivity:8940985] GPI anchor phospholipase D activity of GPLD1 [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8940389] Jassal, Bijay, 2016-09-26
dbId	8940388
displayName	GPLD1 hydrolyses GPI-anchors from proteins
edited	[InstanceEdit:8940389] Jassal, Bijay, 2016-09-26
eventOf	[Pathway:R-HSA-163125] Post-translational modification: synthesis of GPI-anchored proteins - Homo sapiens
input	[DefinedSet:R-HSA-8940978] GPI-anchored proteins [plasma membrane] [SimpleEntity:R-ALL-109276] H2O [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8940678] Structure and expression of the human glycosylphosphatidylinositol phospholipase D1 (GPLD1) gene [LiteratureReference:8941696] A glycan-phosphatidylinositol-specific phospholipase D in human serum [LiteratureReference:8941693] A phospholipase D specific for the phosphatidylinositol anchor of cell-surface proteins is abundant in plasma
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	GPLD1 hydrolyses GPI-anchors from proteins
orthologousEvent	[Reaction:R-SCE-8940388] GPLD1 hydrolyses GPI-anchors from proteins - Saccharomyces cerevisiae [Reaction:R-DDI-8940388] GPLD1 hydrolyses GPI-anchors from proteins - Dictyostelium discoideum [Reaction:R-GGA-8940388] GPLD1 hydrolyses GPI-anchors from proteins - Gallus gallus [Reaction:R-SSC-8940388] GPLD1 hydrolyses GPI-anchors from proteins - Sus scrofa [Reaction:R-BTA-8940388] GPLD1 hydrolyses GPI-anchors from proteins - Bos taurus [Reaction:R-CFA-8940388] GPLD1 hydrolyses GPI-anchors from proteins - Canis familiaris [Reaction:R-RNO-8940388] GPLD1 hydrolyses GPI-anchors from proteins - Rattus norvegicus [Reaction:R-MMU-8940388] GPLD1 hydrolyses GPI-anchors from proteins - Mus musculus
output	[SimpleEntity:R-ALL-2197633] PI [extracellular region] [DefinedSet:R-HSA-8941069] proteins with cleaved GPI-anchors [extracellular region]
releaseDate	2016-12-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8942222] D'Eustachio, Peter, 2016-10-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8940388
summation	[Summation:8940983] Some proteins function at the cell's surface, attached to th...

Referrals

(hasEvent)

[Pathway:R-HSA-163125] Post-translational modification: synthesis of GPI-anchored proteins