Reactome | kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate

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kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate Show undefined attributes

authored	[InstanceEdit:164915] D'Eustachio, P, 2005-07-20 13:46:37
catalystActivity	[CatalystActivity:893618] kynurenine-oxoglutarate transaminase activity of AADAT dimer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:893590] D'Eustachio, P, 2010-07-01
crossReference	[DatabaseIdentifier:12667992] RHEA:20965 [DatabaseIdentifier:9929698] RHEA:20965
dbId	893583
displayName	kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate
edited	[InstanceEdit:164915] D'Eustachio, P, 2005-07-20 13:46:37
eventOf	[Pathway:R-HSA-71240] Tryptophan catabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-893597] 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [mitochondrial] - Homo sapiens
input	[SimpleEntity:R-ALL-113594] 2OG [mitochondrial matrix] [SimpleEntity:R-ALL-893607] L-KYN [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:508552] Crystal structure of human kynurenine aminotransferase II [LiteratureReference:893612] The transamination of kynurenine
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate 2-oxoglutarate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate
orthologousEvent	[Reaction:R-RNO-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Rattus norvegicus [Reaction:R-SCE-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Saccharomyces cerevisiae [Reaction:R-SPO-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Schizosaccharomyces pombe [Reaction:R-DDI-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Dictyostelium discoideum [Reaction:R-GGA-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Gallus gallus [Reaction:R-XTR-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Xenopus tropicalis [Reaction:R-SSC-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Sus scrofa [Reaction:R-BTA-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Bos taurus [Reaction:R-CFA-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Canis familiaris [Reaction:R-MMU-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Mus musculus
output	[SimpleEntity:R-ALL-893617] APDBA [mitochondrial matrix] [SimpleEntity:R-ALL-113552] L-Glu [mitochondrial matrix]
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1004534] Jassal, B, 2010-11-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-893583
summation	[Summation:893573] AADAT dimer localized in the mitochondrial matrix catalyzes ...
updateTrackers	[UpdateTracker:9939700] Update Tracker - [Reaction:893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - v92:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9939700] Update Tracker - [Reaction:893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - v92:[modifyText]
(precedingEvent)	[Reaction:R-HSA-893597] 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [mitochondrial]
(hasEvent)	[Pathway:R-HSA-71240] Tryptophan catabolism

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