Reactome | TFAP2C homodimer:MYC:KDM5B [nucleoplasm]

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TFAP2C homodimer:MYC:KDM5B [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-8865282] TFAP2C homodimer:MYC:KDM5B:CDKN1A gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8865280] TFAP2C homodimer binds the CDKN1A (p21) gene promoter - Homo sapiens
created	[InstanceEdit:8865260] Orlic-Milacic, Marija, 2016-03-21
dbId	8865263
displayName	TFAP2C homodimer:MYC:KDM5B [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-3215031] KDM5B [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-188379] MYC [nucleoplasm] [Complex:R-HSA-8864386] TFAP2C homodimer [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-8865263] TFAP2C homodimer:MYC:KDM5B [nucleoplasm] - Mus musculus [Complex:R-RNO-8865263] TFAP2C homodimer:MYC:KDM5B [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-8865263] TFAP2C homodimer:MYC:KDM5B [nucleoplasm] - Canis familiaris [Complex:R-BTA-8865263] TFAP2C homodimer:MYC:KDM5B [nucleoplasm] - Bos taurus [Complex:R-SSC-8865263] TFAP2C homodimer:MYC:KDM5B [nucleoplasm] - Sus scrofa [Complex:R-DRE-8865263] TFAP2C homodimer:MYC:KDM5B [nucleoplasm] - Danio rerio [Complex:R-XTR-8865263] TFAP2C homodimer:MYC:KDM5B [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-8865263] TFAP2C homodimer:MYC:KDM5B [nucleoplasm] - Gallus gallus [Complex:R-DME-8865263] TFAP2C homodimer:MYC:KDM5B [nucleoplasm] - Drosophila melanogaster
isChimeric	false
literatureReference	[LiteratureReference:8865262] Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A)
maxDepth	3
modified	[InstanceEdit:8871616] Weiser, JD
name	TFAP2C homodimer:MYC:KDM5B
producedByEvent	[Reaction:R-HSA-8865265] TFAP2C homodimer binds MYC and KDM5B - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8865263

Referrals

(activeUnit)	[NegativeGeneExpressionRegulation:R-HSA-8865279] Negative gene expression regulation by 'TFAP2C homodimer:MYC:KDM5B:CDKN1A gene [nucleoplasm]'
(hasComponent)	[Complex:R-HSA-8865282] TFAP2C homodimer:MYC:KDM5B:CDKN1A gene [nucleoplasm]
(input)	[Reaction:R-HSA-8865280] TFAP2C homodimer binds the CDKN1A (p21) gene promoter
(output)	[Reaction:R-HSA-8865265] TFAP2C homodimer binds MYC and KDM5B

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