Reactome | VLDLR binds RELN

Schema > Reaction > Entries

VLDLR binds RELN Show undefined attributes

authored	[InstanceEdit:8854465] Jassal, Bijay, 2016-01-27
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8854465] Jassal, Bijay, 2016-01-27
dbId	8854466
displayName	VLDLR binds RELN
edited	[InstanceEdit:8854465] Jassal, Bijay, 2016-01-27
eventOf	[Pathway:R-HSA-8866376] Reelin signalling pathway - Homo sapiens
followingEvent	[Reaction:R-HSA-8855232] RELN:VLDLR binds DAB1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8854469] RELN [extracellular region] [EntityWithAccessionedSequence:R-HSA-5216079] VLDLR [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8854921] The human reelin gene: isolation, sequencing, and mapping on chromosome 7 [LiteratureReference:8854937] Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation [LiteratureReference:8854935] A decrease of reelin expression as a putative vulnerability factor in schizophrenia
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	VLDLR binds RELN
orthologousEvent	[Reaction:R-GGA-8854466] VLDLR binds RELN - Gallus gallus [Reaction:R-SSC-8854466] VLDLR binds RELN - Sus scrofa [Reaction:R-BTA-8854466] VLDLR binds RELN - Bos taurus [Reaction:R-CFA-8854466] VLDLR binds RELN - Canis familiaris [Reaction:R-RNO-8854466] VLDLR binds RELN - Rattus norvegicus [Reaction:R-MMU-8854466] VLDLR binds RELN - Mus musculus
output	[Complex:R-HSA-8854471] RELN:VLDLR [plasma membrane]
releaseDate	2016-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8866933] D'Eustachio, Peter, 2016-04-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8854466
summation	[Summation:8854920] Reelin (RELN) (DeSilva et al. 1997) is an extracellular matr...

Referrals

(hasEvent)	[Pathway:R-HSA-8866376] Reelin signalling pathway
(precedingEvent)	[Reaction:R-HSA-8855232] RELN:VLDLR binds DAB1