Reactome | HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane]

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HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:8851893] protein tyrosine kinase activity of HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-8851890] MET phosphorylates SHC1-2 - Homo sapiens
created	[InstanceEdit:8851884] Orlic-Milacic, Marija, 2016-01-11
dbId	8851882
displayName	HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane]
hasComponent	[Complex:R-HSA-6806977] HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] [EntityWithAccessionedSequence:R-HSA-1169488] SHC1-2 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-8851882] HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] - Mus musculus [Complex:R-RNO-8851882] HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-8851882] HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] - Canis familiaris [Complex:R-BTA-8851882] HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] - Bos taurus [Complex:R-SSC-8851882] HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] - Sus scrofa [Complex:R-XTR-8851882] HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-8851882] HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:8851883] The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein
maxDepth	5
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	HGF:p-4Y-MET dimer:SHC1-2
producedByEvent	[Reaction:R-HSA-8851888] MET binds SHC1-2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8851882

Referrals

(output)	[Reaction:R-HSA-8851888] MET binds SHC1-2
(input)	[Reaction:R-HSA-8851890] MET phosphorylates SHC1-2
(physicalEntity)	[CatalystActivity:8851893] protein tyrosine kinase activity of HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane]

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