Reactome | NLRP1 oligomerizes

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NLRP1 oligomerizes Show undefined attributes

authored	[InstanceEdit:622270] Jupe, S, 2010-04-22
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:844451] Jupe, S, 2010-05-28
dbId	844438
displayName	NLRP1 oligomerizes
edited	[InstanceEdit:1253354] Jupe, S, 2011-04-28
eventOf	[Pathway:R-HSA-844455] The NLRP1 inflammasome - Homo sapiens
input	[Complex:R-HSA-879207] MDP:NLRP1:ATP [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:844454] Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	NLRP1 oligomerizes
orthologousEvent	[Polymerisation:R-GGA-844438] NLRP1 oligomerizes - Gallus gallus [Polymerisation:R-DRE-844438] NLRP1 oligomerizes - Danio rerio [Polymerisation:R-BTA-844438] NLRP1 oligomerizes - Bos taurus [Polymerisation:R-CFA-844438] NLRP1 oligomerizes - Canis familiaris [Polymerisation:R-RNO-844438] NLRP1 oligomerizes - Rattus norvegicus [Polymerisation:R-MMU-844438] NLRP1 oligomerizes - Mus musculus
output	[Polymer:R-HSA-1296412] MDP:NLRP1:ATP oligomer [cytosol]
precedingEvent	[Reaction:R-HSA-879222] MDP:NLRP1 binds ATP - Homo sapiens
releaseDate	2011-06-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1253355] Kufer, TA, 2011-04-28 [InstanceEdit:1361863] Rittinger, K, 2011-06-06 [InstanceEdit:1361862] Wong, Edmond, 2011-06-06
schemaClass	Polymerisation
species	[Species:48887] Homo sapiens
stId	R-HSA-844438
summation	[Summation:844448] NLRP1 in the presence of Mg2+ was seen to have altered elect...

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[Pathway:R-HSA-844455] The NLRP1 inflammasome

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