Reactome | RNA Polymerase III Holoenzyme [nucleoplasm]

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RNA Polymerase III Holoenzyme [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-113453] Paused RNA Polymerase III Transcription Complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-83755] RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-83803] Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex - Homo sapiens [Reaction:R-HSA-83805] Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex - Homo sapiens [Reaction:R-HSA-76056] Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex - Homo sapiens
created	[InstanceEdit:83685] Gillespie, ME, 2003-11-19 00:00:00
dbId	83716
displayName	RNA Polymerase III Holoenzyme [nucleoplasm]
goCellularComponent	[GO_CellularComponent:17175] RNA polymerase III complex
hasComponent	[Complex:R-HSA-1964428] HsRPC4:HsRPC5 [nucleoplasm] [Complex:R-HSA-1964442] HsRPC6:HsRPC3:HsRPC7 [nucleoplasm] [Complex:R-HSA-1964452] HsRPC8:HsRPC9 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63498] POLR1C [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63500] POLR1D [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83713] POLR2E [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83714] POLR2F [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63523] POLR2H [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63537] POLR2K [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83715] POLR2L [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83700] POLR3A [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83702] POLR3B [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1964461] POLR3K [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Mus musculus [Complex:R-RNO-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Canis familiaris [Complex:R-BTA-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Bos taurus [Complex:R-SSC-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Sus scrofa [Complex:R-DRE-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Danio rerio [Complex:R-DME-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Drosophila melanogaster [Complex:R-DDI-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-83716] RNA Polymerase III Holoenzyme [nucleoplasm] - Saccharomyces cerevisiae
literatureReference	[LiteratureReference:5420843] Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits
maxDepth	4
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	RNA Polymerase III Holoenzyme
producedByEvent	[Reaction:R-HSA-113454] RNA Polymerase III Termination and release of transcribed RNA - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-83716
updateTrackers	[UpdateTracker:9889686] Update Tracker - [Complex:83716] RNA Polymerase III Holoenzyme [nucleoplasm] - v49:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9899681] Update Tracker - [Complex:83716] RNA Polymerase III Holoenzyme [nucleoplasm] - v67:[updateContainedComponent] [UpdateTracker:9871335] Update Tracker - [Complex:83716] RNA Polymerase III Holoenzyme [nucleoplasm] - v39:[add_removeHasComponent] [UpdateTracker:9867078] Update Tracker - [Complex:83716] RNA Polymerase III Holoenzyme [nucleoplasm] - v25:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9889686] Update Tracker - [Complex:83716] RNA Polymerase III Holoenzyme [nucleoplasm] - v49:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9899681] Update Tracker - [Complex:83716] RNA Polymerase III Holoenzyme [nucleoplasm] - v67:[updateContainedComponent] [UpdateTracker:9871335] Update Tracker - [Complex:83716] RNA Polymerase III Holoenzyme [nucleoplasm] - v39:[add_removeHasComponent] [UpdateTracker:9867078] Update Tracker - [Complex:83716] RNA Polymerase III Holoenzyme [nucleoplasm] - v25:[updateContainedComponent]
(output)	[Reaction:R-HSA-113454] RNA Polymerase III Termination and release of transcribed RNA
(hasComponent)	[Complex:R-HSA-113453] Paused RNA Polymerase III Transcription Complex [nucleoplasm] [Complex:R-HSA-83755] RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] [Complex:R-HSA-112151] RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] [Complex:R-HSA-83750] RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Promoter Complex [nucleoplasm] [Complex:R-HSA-112148] RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Open Promoter Complex [nucleoplasm] [Complex:R-HSA-83717] RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex [nucleoplasm] [Complex:R-HSA-112147] RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Open Promoter Complex [nucleoplasm] [Complex:R-HSA-112479] Elongating RNA Polymerase III Transcription Complex [nucleoplasm]
(input)	[Reaction:R-HSA-83803] Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex [Reaction:R-HSA-83805] Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex [Reaction:R-HSA-76056] Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex

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