Reactome | Formation of the CE:GMP intermediate complex

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Formation of the CE:GMP intermediate complex Show undefined attributes

authored	[InstanceEdit:77054] Buratowski, S, 2003-10-15 15:18:41
catalystActivity	[CatalystActivity:77051] mRNA guanylyltransferase activity of Capping complex (hydrolyzed) [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:77054] Buratowski, S, 2003-10-15 15:18:41
dbId	77081
displayName	Formation of the CE:GMP intermediate complex
eventOf	[Pathway:R-HSA-72086] mRNA Capping - Homo sapiens
followingEvent	[Reaction:R-HSA-77083] Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA - Homo sapiens
input	[Complex:R-HSA-77064] Capping complex (hydrolyzed) [nucleoplasm] [SimpleEntity:R-ALL-113571] GTP [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:77482] Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme.
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Formation of the CE:GMP intermediate complex
orthologousEvent	[Reaction:R-PFA-77081] Formation of the CE:GMP intermediate complex - Plasmodium falciparum [Reaction:R-SCE-77081] Formation of the CE:GMP intermediate complex - Saccharomyces cerevisiae [Reaction:R-SPO-77081] Formation of the CE:GMP intermediate complex - Schizosaccharomyces pombe [Reaction:R-DDI-77081] Formation of the CE:GMP intermediate complex - Dictyostelium discoideum [Reaction:R-CEL-77081] Formation of the CE:GMP intermediate complex - Caenorhabditis elegans [Reaction:R-DME-77081] Formation of the CE:GMP intermediate complex - Drosophila melanogaster [Reaction:R-XTR-77081] Formation of the CE:GMP intermediate complex - Xenopus tropicalis [Reaction:R-DRE-77081] Formation of the CE:GMP intermediate complex - Danio rerio [Reaction:R-SSC-77081] Formation of the CE:GMP intermediate complex - Sus scrofa [Reaction:R-BTA-77081] Formation of the CE:GMP intermediate complex - Bos taurus [Reaction:R-CFA-77081] Formation of the CE:GMP intermediate complex - Canis familiaris [Reaction:R-RNO-77081] Formation of the CE:GMP intermediate complex - Rattus norvegicus [Reaction:R-MMU-77081] Formation of the CE:GMP intermediate complex - Mus musculus
output	[Complex:R-HSA-77065] Capping complex (intermediate) [nucleoplasm] [SimpleEntity:R-ALL-111349] GDP [nucleoplasm]
precedingEvent	[Reaction:R-HSA-77078] Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-77081
summation	[Summation:77082] A highly conserved lysine within the guanylyltransferase (GT...

Referrals

(hasEvent)	[Pathway:R-HSA-72086] mRNA Capping
(precedingEvent)	[Reaction:R-HSA-77083] Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA