Reactome | mRNA (N6-adenosine)-methyltransferase [nucleoplasm]

Schema > Complex > Entries

mRNA (N6-adenosine)-methyltransferase [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:72094] mRNA m(6)A methyltransferase activity of mRNA (N6-adenosine)-methyltransferase [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
dbId	72093
displayName	mRNA (N6-adenosine)-methyltransferase [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-72092] METTL14 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-72091] METTL3 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-6789461] WTAP [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - Mus musculus [Complex:R-RNO-72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - Rattus norvegicus [Complex:R-BTA-72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - Bos taurus [Complex:R-SSC-72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - Sus scrofa [Complex:R-DRE-72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - Danio rerio [Complex:R-XTR-72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - Xenopus tropicalis [Complex:R-DME-72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - Drosophila melanogaster [Complex:R-PFA-72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - Plasmodium falciparum
literatureReference	[LiteratureReference:6789442] A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation [LiteratureReference:6789452] Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase [LiteratureReference:6789470] Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites
maxDepth	2
modified	[InstanceEdit:6789476] May, Bruce, 2015-07-31
name	mRNA (N6-adenosine)-methyltransferase METTL3:METTL14:WTAP
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-72093
updateTrackers	[UpdateTracker:9892611] Update Tracker - [Complex:72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - v54:[addHasComponent, addLiteratureReference, addName]

Referrals

(updatedInstance)	[UpdateTracker:9892611] Update Tracker - [Complex:72093] mRNA (N6-adenosine)-methyltransferase [nucleoplasm] - v54:[addHasComponent, addLiteratureReference, addName]
(physicalEntity)	[CatalystActivity:72094] mRNA m(6)A methyltransferase activity of mRNA (N6-adenosine)-methyltransferase [nucleoplasm]

© 2026 Reactome

Cite Us!