Reactome | CSTF heterotrimer [nucleoplasm]

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CSTF heterotrimer [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-112161] CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-77590] Recruitment of CstF to the CPSF Bound Pre-mRNA - Homo sapiens
dbId	72006
displayName	CSTF heterotrimer [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-72001] CSTF1 [nucleoplasm] [DefinedSet:R-HSA-8938794] CSTF2,CSTF2T [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-72005] CSTF3 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-72006] CSTF heterotrimer [nucleoplasm] - Mus musculus [Complex:R-RNO-72006] CSTF heterotrimer [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-72006] CSTF heterotrimer [nucleoplasm] - Canis familiaris [Complex:R-BTA-72006] CSTF heterotrimer [nucleoplasm] - Bos taurus [Complex:R-SSC-72006] CSTF heterotrimer [nucleoplasm] - Sus scrofa [Complex:R-DRE-72006] CSTF heterotrimer [nucleoplasm] - Danio rerio [Complex:R-XTR-72006] CSTF heterotrimer [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-72006] CSTF heterotrimer [nucleoplasm] - Gallus gallus [Complex:R-DME-72006] CSTF heterotrimer [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-72006] CSTF heterotrimer [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-72006] CSTF heterotrimer [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-72006] CSTF heterotrimer [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-72006] CSTF heterotrimer [nucleoplasm] - Saccharomyces cerevisiae [Complex:R-PFA-72006] CSTF heterotrimer [nucleoplasm] - Plasmodium falciparum
literatureReference	[LiteratureReference:8938785] Overlapping and distinct functions of CstF64 and CstF64? in mammalian mRNA 3' processing [LiteratureReference:8938804] Complex protein interactions within the human polyadenylation machinery identify a novel component
maxDepth	3
modified	[InstanceEdit:9971227] Orlic-Milacic, Marija, 2025-11-05
name	CSTF heterotrimer Cleavage Stimulation Factor heterotrimer
producedByEvent	[Reaction:R-HSA-77593] Cleavage and polyadenylation of Intronless Pre-mRNA - Homo sapiens [Reaction:R-HSA-77592] Cleavage of Intronless Pre-mRNA at 3'-end - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-72006
updateTrackers	[UpdateTracker:9972838] Update Tracker - [Complex:72006] CSTF heterotrimer [nucleoplasm] - v95:[modifyName] [UpdateTracker:9867179] Update Tracker - [Complex:72006] CstF [nucleoplasm] - v25:[updateContainedComponent] [UpdateTracker:9895365] Update Tracker - [Complex:72006] CstF [nucleoplasm] - v59:[addLiteratureReference, add_removeHasComponent]

Referrals

(updatedInstance)	[UpdateTracker:9972838] Update Tracker - [Complex:72006] CSTF heterotrimer [nucleoplasm] - v95:[modifyName] [UpdateTracker:9867179] Update Tracker - [Complex:72006] CstF [nucleoplasm] - v25:[updateContainedComponent] [UpdateTracker:9895365] Update Tracker - [Complex:72006] CstF [nucleoplasm] - v59:[addLiteratureReference, add_removeHasComponent]
(output)	[Reaction:R-HSA-77592] Cleavage of Intronless Pre-mRNA at 3'-end [Reaction:R-HSA-77593] Cleavage and polyadenylation of Intronless Pre-mRNA
(input)	[Reaction:R-HSA-77590] Recruitment of CstF to the CPSF Bound Pre-mRNA
(hasComponent)	[Complex:R-HSA-112161] CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] [Complex:R-HSA-9970107] CSTF hexamer [nucleoplasm]

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