Reactome | U2 snRNP [nucleoplasm]

Schema > Complex > Entries

U2 snRNP [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-72074] Spliceosomal Intermediate C Complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-9769528] Spliceosomal Pre-B complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-9943563] CHD1:H3K4 nucleosome:FACT complex:U2 snRNP complex:PAF1C complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-9770126] Spliceosomal B complex [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9943567] CHD1:H3K4me3 interacts with post-initiation transcription complexes - Homo sapiens [BlackBoxEvent:R-HSA-9770129] Formation of the Spliceosomal A complex - Homo sapiens
dbId	71980
displayName	U2 snRNP [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-8865901] CHERP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5688096] DDX46 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5688097] DHX15 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-66652] PHF5A [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8865910] PUF60 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8865891] RBM17 [nucleoplasm] [Complex:R-HSA-71967] SF3A [nucleoplasm] [Complex:R-HSA-71976] SF3B [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8865958] SMNDC1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-71958] SNRPA1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-71960] SNRPB2 [nucleoplasm] [Complex:R-HSA-8871336] U2 Sm core complex [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-71956] U2 snRNA [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8865950] U2SURP [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-71980] U2 snRNP [nucleoplasm] - Mus musculus [Complex:R-RNO-71980] U2 snRNP [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-71980] U2 snRNP [nucleoplasm] - Canis familiaris [Complex:R-BTA-71980] U2 snRNP [nucleoplasm] - Bos taurus [Complex:R-SSC-71980] U2 snRNP [nucleoplasm] - Sus scrofa [Complex:R-DRE-71980] U2 snRNP [nucleoplasm] - Danio rerio [Complex:R-XTR-71980] U2 snRNP [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-71980] U2 snRNP [nucleoplasm] - Gallus gallus [Complex:R-DME-71980] U2 snRNP [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-71980] U2 snRNP [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-71980] U2 snRNP [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-71980] U2 snRNP [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-PFA-71980] U2 snRNP [nucleoplasm] - Plasmodium falciparum
literatureReference	[LiteratureReference:8865932] Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein [LiteratureReference:8865895] Dynamic protein-protein interaction wiring of the human spliceosome
maxDepth	4
modified	[InstanceEdit:8871337] May, Bruce, 2016-05-14
name	U2 snRNP
negativelyRegulates	[NegativeRegulation:9970631] Negative regulation by 'U2 snRNP [nucleoplasm]'
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-71980
updateTrackers	[UpdateTracker:9894425] Update Tracker - [Complex:71980] U2 snRNP [nucleoplasm] - v57:[addLiteratureReference, add_removeHasComponent, updateContainedComponent] [UpdateTracker:9863780] Update Tracker - [Complex:71980] U2 snRNP [nucleoplasm] - v20:[add_removeHasComponent, updateContainedComponent]

Referrals

(hasComponent)	[Complex:R-HSA-72074] Spliceosomal Intermediate C Complex [nucleoplasm] [Complex:R-HSA-9769560] Spliceosomal Bact complex [nucleoplasm] [Complex:R-HSA-9770126] Spliceosomal B complex [nucleoplasm] [Complex:R-HSA-9769528] Spliceosomal Pre-B complex [nucleoplasm] [Complex:R-HSA-9970412] Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] [Complex:R-HSA-9770140] Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] [Complex:R-HSA-9943563] CHD1:H3K4 nucleosome:FACT complex:U2 snRNP complex:PAF1C complex [nucleoplasm] [Complex:R-HSA-9970323] Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] [Complex:R-HSA-9970283] Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] [Complex:R-HSA-9970253] Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] [Complex:R-HSA-9970387] Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] [Complex:R-HSA-9970290] Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] [Complex:R-HSA-9970401] Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] [Complex:R-HSA-9970285] Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm]
(input)	[BlackBoxEvent:R-HSA-9770129] Formation of the Spliceosomal A complex [Reaction:R-HSA-9943567] CHD1:H3K4me3 interacts with post-initiation transcription complexes
(regulator)	[NegativeRegulation:9970631] Negative regulation by 'U2 snRNP [nucleoplasm]'
(updatedInstance)	[UpdateTracker:9894425] Update Tracker - [Complex:71980] U2 snRNP [nucleoplasm] - v57:[addLiteratureReference, add_removeHasComponent, updateContainedComponent] [UpdateTracker:9863780] Update Tracker - [Complex:71980] U2 snRNP [nucleoplasm] - v20:[add_removeHasComponent, updateContainedComponent]

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