Reactome | 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate

Schema > Reaction > Entries

4-imidazolone-5-propanoate + H2O => N-formiminoglutamate Show undefined attributes

authored	[InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
catalystActivity	[CatalystActivity:70905] hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides of AMDHD1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
crossReference	[DatabaseIdentifier:12667937] RHEA:23661 [DatabaseIdentifier:9925949] RHEA:23661
dbId	70906
displayName	4-imidazolone-5-propanoate + H2O => N-formiminoglutamate
edited	[InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
eventOf	[Pathway:R-HSA-70921] Histidine catabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-70920] N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate - Homo sapiens
input	[SimpleEntity:R-ALL-34979] 4I-5PROA [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:200020] Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	4-imidazolone-5-propanoate + H2O => N-formiminoglutamate 4-imidazolone-5-propanoate + H2O => N-formimidoyl-L-glutamate
orthologousEvent	[Reaction:R-RNO-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Rattus norvegicus [Reaction:R-DDI-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Dictyostelium discoideum [Reaction:R-CEL-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Caenorhabditis elegans [Reaction:R-GGA-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Gallus gallus [Reaction:R-XTR-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Xenopus tropicalis [Reaction:R-DRE-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Danio rerio [Reaction:R-SSC-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Sus scrofa [Reaction:R-BTA-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Bos taurus [Reaction:R-CFA-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Canis familiaris [Reaction:R-MMU-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Mus musculus
output	[SimpleEntity:R-ALL-30158] NF-Glu [cytosol]
precedingEvent	[Reaction:R-HSA-70903] urocanate + H2O => 4-imidazolone-5-propanoate - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9927660] D'Eustachio, Peter, 2024-11-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-70906
summation	[Summation:178346] Cytosolic imidazolonepropionase catalyzes the hydrolysis of ...
updateTrackers	[UpdateTracker:9790878] Update Tracker - [Reaction:70906] 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ - v32:[modifyText] [UpdateTracker:9790551] Update Tracker - [Reaction:70906] 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ - v33:[addOutput] [UpdateTracker:9792348] Update Tracker - [Reaction:70906] 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ - v22:[addLiteratureReference, modifyText] [UpdateTracker:9928491] Update Tracker - [Reaction:70906] 4-imidazolone-5-propionate + H2O => N-formiminoglutamate - v91:[addOutput]

Referrals

(updatedInstance)	[UpdateTracker:9790878] Update Tracker - [Reaction:70906] 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ - v32:[modifyText] [UpdateTracker:9790551] Update Tracker - [Reaction:70906] 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ - v33:[addOutput] [UpdateTracker:9792348] Update Tracker - [Reaction:70906] 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ - v22:[addLiteratureReference, modifyText] [UpdateTracker:9928491] Update Tracker - [Reaction:70906] 4-imidazolone-5-propionate + H2O => N-formiminoglutamate - v91:[addOutput]
(hasEvent)	[Pathway:R-HSA-70921] Histidine catabolism
(precedingEvent)	[Reaction:R-HSA-70920] N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate

Cite Us!