Reactome | K63 polyubiquitinated RIP2 associates with the TAK1 complex

Schema > Reaction > Entries

K63 polyubiquitinated RIP2 associates with the TAK1 complex Show undefined attributes

authored	[InstanceEdit:622270] Jupe, S, 2010-04-22
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:688983] Jupe, S, 2010-05-07
dbId	688985
displayName	K63 polyubiquitinated RIP2 associates with the TAK1 complex
edited	[InstanceEdit:1253354] Jupe, S, 2011-04-28
eventOf	[Pathway:R-HSA-168638] NOD1/2 Signaling Pathway - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-450187] TAK1 is activated within the TAK1 complex - Homo sapiens [BlackBoxEvent:R-HSA-706479] TAK1 is activated - Homo sapiens
input	[Complex:R-HSA-706480] PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] [Complex:R-HSA-8947970] TAK1 complex [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:688135] A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	K63 polyubiquitinated RIP2 associates with the TAK1 complex
orthologousEvent	[Reaction:R-XTR-688985] K63 polyubiquitinated RIP2 associates with the TAK1 complex - Xenopus tropicalis [Reaction:R-BTA-688985] K63 polyubiquitinated RIP2 associates with the TAK1 complex - Bos taurus [Reaction:R-CFA-688985] K63 polyubiquitinated RIP2 associates with the TAK1 complex - Canis familiaris [Reaction:R-RNO-688985] K63 polyubiquitinated RIP2 associates with the TAK1 complex - Rattus norvegicus [Reaction:R-MMU-688985] K63 polyubiquitinated RIP2 associates with the TAK1 complex - Mus musculus
output	[Complex:R-HSA-706478] PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane]
precedingEvent	[Reaction:R-HSA-688137] RIP2 is K63 polyubiquitinated - Homo sapiens
releaseDate	2011-06-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1253355] Kufer, TA, 2011-04-28 [InstanceEdit:1361863] Rittinger, K, 2011-06-06 [InstanceEdit:1361862] Wong, Edmond, 2011-06-06
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-688985
summation	[Summation:688992] K63-polyubiquitinated RIP2 is able to recruit the components...
updateTrackers	[UpdateTracker:9782681] Update Tracker - [Reaction:688985] K63 polyubiquitinated RIP2 associates with the TAK1 complex - v59:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9782681] Update Tracker - [Reaction:688985] K63 polyubiquitinated RIP2 associates with the TAK1 complex - v59:[add_removeInput]
(precedingEvent)	[BlackBoxEvent:R-HSA-450187] TAK1 is activated within the TAK1 complex [BlackBoxEvent:R-HSA-706479] TAK1 is activated
(hasEvent)	[Pathway:R-HSA-168638] NOD1/2 Signaling Pathway

Cite Us!