Reactome | NSF and SNAPs bind cis-SNARE at the ER membrane

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NSF and SNAPs bind cis-SNARE at the ER membrane Show undefined attributes

authored	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
category	binding
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:6811424] Rothfels, Karen, 2015-11-19
dbId	6811425
displayName	NSF and SNAPs bind cis-SNARE at the ER membrane
edited	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
eventOf	[Pathway:R-HSA-6811434] COPI-dependent Golgi-to-ER retrograde traffic - Homo sapiens
followingEvent	[Reaction:R-HSA-6811422] NSF ATPase activity dissociates cis-SNARE at the ER - Homo sapiens
input	[Complex:R-HSA-2193131] NSF hexamer [cytosol] [Complex:R-HSA-6811343] SEC22B:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane] 3 × [CandidateSet:R-HSA-5694313] SNAPs [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5688473] Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles [LiteratureReference:5688461] A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion [LiteratureReference:5689380] SNAREs--engines for membrane fusion [LiteratureReference:5688193] Membrane fusion: grappling with SNARE and SM proteins
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	NSF and SNAPs bind cis-SNARE at the ER membrane
orthologousEvent	[Reaction:R-SCE-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Saccharomyces cerevisiae [Reaction:R-SPO-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Schizosaccharomyces pombe [Reaction:R-DDI-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Dictyostelium discoideum [Reaction:R-CEL-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Caenorhabditis elegans [Reaction:R-DME-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Drosophila melanogaster [Reaction:R-GGA-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Gallus gallus [Reaction:R-XTR-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Xenopus tropicalis [Reaction:R-DRE-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Danio rerio [Reaction:R-SSC-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Sus scrofa [Reaction:R-BTA-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Bos taurus [Reaction:R-CFA-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Canis familiaris [Reaction:R-RNO-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Rattus norvegicus [Reaction:R-MMU-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Mus musculus
output	[Complex:R-HSA-6811344] SEC22B:STX18:USE1:BNIP1L:3xSNAPs:NSF hexamer [endoplasmic reticulum membrane]
precedingEvent	[BlackBoxEvent:R-HSA-6811427] COPI vesicle uncoating at the ER - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855182] Gillespie, Marc E, 2016-02-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6811425
summation	[Summation:6811276] After membrane fusion, the 4-membered cis-SNARE complex is d...

Referrals

(precedingEvent)	[Reaction:R-HSA-6811422] NSF ATPase activity dissociates cis-SNARE at the ER
(hasEvent)	[Pathway:R-HSA-6811434] COPI-dependent Golgi-to-ER retrograde traffic

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