Reactome | AP-1:p-S15,S20-TP53 Tetramer:MSH2 Gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6806562] Orlic-Milacic, Marija, 2015-10-23
dbId	6806565
displayName	AP-1:p-S15,S20-TP53 Tetramer:MSH2 Gene [nucleoplasm]
hasComponent	[DefinedSet:R-HSA-6806560] AP-1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-6806564] MSH2 Gene [nucleoplasm] [Complex:R-HSA-3222171] p-S15,S20-TP53 Tetramer [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:6806409] p53 and c-Jun functionally synergize in the regulation of the DNA repair gene hMSH2 in response to UV
maxDepth	4
name	AP-1:p-S15,S20-TP53 Tetramer:MSH2 Gene
positivelyRegulates	[PositiveGeneExpressionRegulation:R-HSA-6806569] Positive gene expression regulation by 'AP-1:p-S15,S20-TP53 Tetramer:MSH2 Gene [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-6806412] TP53 and AP-1 bind the MSH2 promoter - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6806565

(output)	[Reaction:R-HSA-6806412] TP53 and AP-1 bind the MSH2 promoter
(regulator)	[PositiveGeneExpressionRegulation:R-HSA-6806569] Positive gene expression regulation by 'AP-1:p-S15,S20-TP53 Tetramer:MSH2 Gene [nucleoplasm]'

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