Reactome | APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol]

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APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:266291] cysteine-type endopeptidase activity of APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-114259] Cleavage of Procaspase?9 to caspase?9 - Homo sapiens
created	[InstanceEdit:6804647] Shamovsky, Veronica, 2015-10-13
dbId	6804630
displayName	APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol]
hasComponent	7 × [Complex:R-HSA-114253] APAF1:CYCS [cytosol] 2 × [Complex:R-HSA-6804623] CASP9(1-416) dimer [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-6804630] APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] - Mus musculus [Complex:R-RNO-6804630] APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] - Rattus norvegicus [Complex:R-CFA-6804630] APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] - Canis familiaris [Complex:R-BTA-6804630] APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] - Bos taurus [Complex:R-SSC-6804630] APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] - Sus scrofa [Complex:R-DRE-6804630] APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] - Danio rerio [Complex:R-XTR-6804630] APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] - Xenopus tropicalis [Complex:R-GGA-6804630] APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] - Gallus gallus [Complex:R-DME-6804630] APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] - Drosophila melanogaster
literatureReference	[LiteratureReference:6804597] Structure of an apoptosome-procaspase-9 CARD complex [LiteratureReference:9627385] A near atomic structure of the active human apoptosome
maxDepth	3
memberOf	[DefinedSet:R-HSA-6804662] Apoptosome [cytosol] - Homo sapiens
modified	[InstanceEdit:9627414] Shamovsky, Veronica, 2018-11-02
name	APAF1:CYCS:ATP:CASP9(1-416)dimer (APAF1:cytochrome C:ATP)heptamer:Procaspase-9 dimer
producedByEvent	[Reaction:R-HSA-9627056] Procaspase 9 forms dimer - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6804630

Referrals

(hasMember)	[DefinedSet:R-HSA-6804662] Apoptosome [cytosol]
(output)	[Reaction:R-HSA-9627056] Procaspase 9 forms dimer
(input)	[Reaction:R-HSA-114259] Cleavage of Procaspase?9 to caspase?9
(physicalEntity)	[CatalystActivity:266291] cysteine-type endopeptidase activity of APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol]

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