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Schema
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Reaction
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Entries
RNASEs bind bacterial LPS, PGN
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authored
[InstanceEdit:6803156] Shamovsky, Veronica, 2015-10-05
category
binding
compartment
[Compartment:984] extracellular region
[Compartment:25409] peptidoglycan-based cell wall
created
[InstanceEdit:6803137] Shamovsky, Veronica, 2015-10-04
dbId
6803063
displayName
RNASEs bind bacterial LPS, PGN
edited
[InstanceEdit:8935852] Shamovsky, Veronica, 2016-08-15
entityOnOtherCell
[DefinedSet:R-ALL-6803074] LPS, PGN [peptidoglycan-based cell wall]
eventOf
[Pathway:R-HSA-6803157] Antimicrobial peptides - Homo sapiens
input
[DefinedSet:R-ALL-6803074] LPS, PGN [peptidoglycan-based cell wall]
[CandidateSet:R-HSA-6803116] RNASE3,RNASE7,RNASE6,(RNASE8) [extracellular region]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:6803058] Ribonuclease 7, an antimicrobial peptide upregulated during infection, contributes to microbial defense of the human urinary tract
[LiteratureReference:6803113] Comparison of human RNase 3 and RNase 7 bactericidal action at the Gram-negative and Gram-positive bacterial cell wall
[LiteratureReference:6803046] Antimicrobial RNases in cutaneous defense
[LiteratureReference:6803083] Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract
[LiteratureReference:8866729] Identification of RNase 8 as a novel human antimicrobial protein
[LiteratureReference:8866728] The antipathogen activities of eosinophil cationic protein
[LiteratureReference:8947985] Insights into the Antimicrobial Mechanism of Action of Human RNase6: Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation
maxDepth
1
modified
[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name
RNASEs bind bacterial LPS, PGN
orthologousEvent
[Reaction:R-MMU-6803063] RNASEs bind bacterial LPS, PGN - Mus musculus
[Reaction:R-GGA-6803063] RNASEs bind bacterial LPS, PGN - Gallus gallus
[Reaction:R-DRE-6803063] RNASEs bind bacterial LPS, PGN - Danio rerio
[Reaction:R-SSC-6803063] RNASEs bind bacterial LPS, PGN - Sus scrofa
[Reaction:R-BTA-6803063] RNASEs bind bacterial LPS, PGN - Bos taurus
[Reaction:R-RNO-6803063] RNASEs bind bacterial LPS, PGN - Rattus norvegicus
output
[Complex:R-HSA-6803051] RNASEs 3,6,7,(8):LPS,PGN [extracellular region]
releaseDate
2016-09-19
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:8933035] Hains, David S, 2016-08-02
[InstanceEdit:8867536] Jupe, Steve, 2016-04-15
[InstanceEdit:8947982] Boix, Ester, 2016-11-07
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-6803063
summation
[Summation:6803052] Ribonucleases (RNase) 3, 6 and 7, which belong to the RNase ...
updateTrackers
[UpdateTracker:9782054] Update Tracker - [Reaction:6803063] RNASEs bind bacterial LPS, PGN - v59:[addLiteratureReference, modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9782054] Update Tracker - [Reaction:6803063] RNASEs bind bacterial LPS, PGN - v59:[addLiteratureReference, modifyText]
(hasEvent)
[Pathway:R-HSA-6803157] Antimicrobial peptides
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