Reactome | S100A7 or S100A7A binds Zn2+

Schema > Reaction > Entries

S100A7 or S100A7A binds Zn2+ Show undefined attributes

authored	[InstanceEdit:6803156] Shamovsky, Veronica, 2015-10-05
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:6798553] Shamovsky, Veronica, 2015-09-19
dbId	6798489
displayName	S100A7 or S100A7A binds Zn2+
edited	[InstanceEdit:8935852] Shamovsky, Veronica, 2016-08-15
eventOf	[Pathway:R-HSA-6799990] Metal sequestration by antimicrobial proteins - Homo sapiens
input	[Complex:R-HSA-6798557] S100A7, S100A7A:Ca2+ [extracellular region] 2 × [SimpleEntity:R-ALL-158417] Zn2+ [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6798498] Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states [LiteratureReference:6798548] Identification and characterization of binding sites on S100A7, a participant in cancer and inflammation pathways [LiteratureReference:6798457] Structural characterization of S100A15 reveals a novel zinc coordination site among S100 proteins and altered surface chemistry with functional implications for receptor binding
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	S100A7 or S100A7A binds Zn2+ S100A7/S100A15 binds Zn2+
orthologousEvent	[Reaction:R-XTR-6798489] S100A7 or S100A7A binds Zn2+ - Xenopus tropicalis [Reaction:R-SSC-6798489] S100A7 or S100A7A binds Zn2+ - Sus scrofa [Reaction:R-BTA-6798489] S100A7 or S100A7A binds Zn2+ - Bos taurus
output	[Complex:R-HSA-6798500] S100A7, S100A7A:Ca2+:Zn2+ [extracellular region]
releaseDate	2016-09-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8933035] Hains, David S, 2016-08-02 [InstanceEdit:8867536] Jupe, Steve, 2016-04-15
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6798489
summation	[Summation:6798401] Human S100A7 (known as psoriasin) is expressed in epidermal ...
updateTrackers	[UpdateTracker:9864170] Update Tracker - [Reaction:6798489] S100A7 or S100A7A binds Zn2+ - v88:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9864170] Update Tracker - [Reaction:6798489] S100A7 or S100A7A binds Zn2+ - v88:[modifyText]
(hasEvent)	[Pathway:R-HSA-6799990] Metal sequestration by antimicrobial proteins