Reactome | HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm]

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HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-606282] CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA:H4 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-606326] HJURP:CENPA complex localizes to the centromere - Homo sapiens
created	[InstanceEdit:606312] May, B, 2010-04-17
dbId	606319
displayName	HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm]
hasComponent	[Complex:R-HSA-606291] CENPA:H4 Tetramer [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-606331] HJURP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-606320] NPM1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-212223] RBBP4 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-212227] RBBP7 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-418323] RUVBL1 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-606319] HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] - Mus musculus [Complex:R-RNO-606319] HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-606319] HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] - Canis familiaris [Complex:R-BTA-606319] HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] - Bos taurus [Complex:R-SSC-606319] HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] - Sus scrofa [Complex:R-XTR-606319] HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] - Xenopus tropicalis
isChimeric	false
literatureReference	[LiteratureReference:606290] HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres [LiteratureReference:606283] Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP [LiteratureReference:606307] HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres
maxDepth	3
modified	[InstanceEdit:5633525] May, Bruce, 2014-11-02
name	HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 HJURP:CENPA Complex
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-606319

Referrals

(input)	[Reaction:R-HSA-606326] HJURP:CENPA complex localizes to the centromere
(hasComponent)	[Complex:R-HSA-606282] CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA:H4 [nucleoplasm]

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