Reactome | CASP8(1-479):UL36 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5692540] Shamovsky, Veronica, 2015-05-12
crossReference	[DatabaseIdentifier:12020762] Mondo:0005108
dbId	5692539
disease	[Disease:3134794] viral infectious disease
displayName	CASP8(1-479):UL36 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-HSA-57031] CASP8(1-479) [cytosol] [EntityWithAccessionedSequence:R-HCY-5692537] UL36 [cytosol]
inDisease	true
isChimeric	false
literatureReference	[LiteratureReference:5692545] A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation
maxDepth	2
modified	[InstanceEdit:9794196] Shamovsky, Veronica, 2022-06-27
name	CASP8(1-479):UL36 CASP8(1-479):vICA
negativelyRegulates	[NegativeRegulation:R-HSA-5692563] Negative regulation by 'CASP8(1-479):UL36 [cytosol]'
producedByEvent	[Reaction:R-HSA-5692550] Viral inhibitor of caspase-8 activation (UL36) binds caspase-8 - Homo sapiens
relatedSpecies	[Species:2671791] Human cytomegalovirus
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5692539
updateTrackers	[UpdateTracker:9904419] Update Tracker - [Complex:5692539] CASP8(1-479):UL36 [cytosol] - v82:[addDisease] [UpdateTracker:9895875] Update Tracker - [Complex:5692539] CASP8(1-479):UL36 [cytosol] - v60:[removeSpecies]

(updatedInstance)	[UpdateTracker:9904419] Update Tracker - [Complex:5692539] CASP8(1-479):UL36 [cytosol] - v82:[addDisease] [UpdateTracker:9895875] Update Tracker - [Complex:5692539] CASP8(1-479):UL36 [cytosol] - v60:[removeSpecies]
(output)	[Reaction:R-HSA-5692550] Viral inhibitor of caspase-8 activation (UL36) binds caspase-8
(regulator)	[NegativeRegulation:R-HSA-5692563] Negative regulation by 'CASP8(1-479):UL36 [cytosol]'

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