Reactome | Ovarian tumor domain proteases

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Ovarian tumor domain proteases Show undefined attributes

authored	[InstanceEdit:5688416] Jupe, Steve, 2015-04-16
created	[InstanceEdit:5689906] Jupe, Steve, 2015-04-24
dbId	5689896
displayName	Ovarian tumor domain proteases
edited	[InstanceEdit:8869523] Jupe, Steve, 2016-05-05
eventOf	[Pathway:R-HSA-5688426] Deubiquitination - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-5690843] OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA - Homo sapiens [Reaction:R-HSA-6783238] OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 - Homo sapiens [Reaction:R-HSA-688136] TNFAIP3 (A20) deubiquitinates RIP2 - Homo sapiens [Reaction:R-HSA-5690856] TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 - Homo sapiens [Reaction:R-HSA-5690827] TNFAIP3 (A20) ubiquitinates RIPK1 - Homo sapiens [Reaction:R-HSA-5690845] TNIPs bind TNFAIP3 (A20) - Homo sapiens [Reaction:R-HSA-5690870] OTUD7B,TNFAIP3 deubiquitinate TRAF6 - Homo sapiens [Reaction:R-HSA-8869506] TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 - Homo sapiens [Reaction:R-HSA-936381] OTUD5 deubiquitinates TRAF3 - Homo sapiens [Reaction:R-HSA-6781953] YOD1 binds VCP - Homo sapiens [Reaction:R-HSA-6781905] ZRANB1 binds APC - Homo sapiens [Reaction:R-HSA-8865182] OTUD7A hydrolyses K11diUb - Homo sapiens [Reaction:R-HSA-8873946] OTUD3 deubiquitinates PTEN - Homo sapiens [Reaction:R-HSA-8940100] CDK1 phosphorylates VCPIP1 - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2019-09-09
literatureReference	[LiteratureReference:8862421] OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Ovarian tumor domain proteases
orthologousEvent	[Pathway:R-PFA-5689896] Ovarian tumor domain proteases - Plasmodium falciparum [Pathway:R-SCE-5689896] Ovarian tumor domain proteases - Saccharomyces cerevisiae [Pathway:R-SPO-5689896] Ovarian tumor domain proteases - Schizosaccharomyces pombe [Pathway:R-DDI-5689896] Ovarian tumor domain proteases - Dictyostelium discoideum [Pathway:R-CEL-5689896] Ovarian tumor domain proteases - Caenorhabditis elegans [Pathway:R-DME-5689896] Ovarian tumor domain proteases - Drosophila melanogaster [Pathway:R-GGA-5689896] Ovarian tumor domain proteases - Gallus gallus [Pathway:R-XTR-5689896] Ovarian tumor domain proteases - Xenopus tropicalis [Pathway:R-DRE-5689896] Ovarian tumor domain proteases - Danio rerio [Pathway:R-SSC-5689896] Ovarian tumor domain proteases - Sus scrofa [Pathway:R-BTA-5689896] Ovarian tumor domain proteases - Bos taurus [Pathway:R-CFA-5689896] Ovarian tumor domain proteases - Canis familiaris [Pathway:R-RNO-5689896] Ovarian tumor domain proteases - Rattus norvegicus [Pathway:R-MMU-5689896] Ovarian tumor domain proteases - Mus musculus
releaseDate	2016-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8871339] Meldal, Birgit, 2016-05-16
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5689896
summation	[Summation:5689887] Humans have 16 Ovarian tumour domain (OTU) family DUBs that ...
updateTrackers	[UpdateTracker:9777520] Update Tracker - [Pathway:5689896] Ovarian tumor domain proteases - v70:[modifyText] [UpdateTracker:9781570] Update Tracker - [Pathway:5689896] Ovarian tumor domain proteases - v60:[addHasEvent] [UpdateTracker:9782783] Update Tracker - [Pathway:5689896] Ovarian tumor domain proteases - v58:[addHasEvent]

Referrals

(updatedInstance)	[UpdateTracker:9777520] Update Tracker - [Pathway:5689896] Ovarian tumor domain proteases - v70:[modifyText] [UpdateTracker:9781570] Update Tracker - [Pathway:5689896] Ovarian tumor domain proteases - v60:[addHasEvent] [UpdateTracker:9782783] Update Tracker - [Pathway:5689896] Ovarian tumor domain proteases - v58:[addHasEvent]
(hasEvent)	[Pathway:R-HSA-5688426] Deubiquitination

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