Reactome | Defective SFTPA2 causes IPF

Schema > Pathway > Entries

authored	[InstanceEdit:5687869] Jassal, Bijay, 2015-04-10
created	[InstanceEdit:5687869] Jassal, Bijay, 2015-04-10
crossReference	[DatabaseIdentifier:12020948] Mondo:0700081
dbId	5687868
disease	[Disease:5687878] idiopathic pulmonary fibrosis [Disease:5683679] newborn respiratory distress syndrome
displayName	Defective SFTPA2 causes IPF
edited	[InstanceEdit:5687869] Jassal, Bijay, 2015-04-10
eventOf	[Pathway:R-HSA-5687613] Diseases associated with surfactant metabolism - Homo sapiens
hasDiagram	true
hasEHLD	false
hasEvent	[FailedReaction:R-HSA-5687875] Defective SFTPA2 does not translocate from ER membrane to extracellular region - Homo sapiens
isInDisease	true
isInferred	false
lastUpdatedDate	2018-12-13
literatureReference	[LiteratureReference:5687989] Idiopathic pulmonary fibrosis [LiteratureReference:5687987] Pulmonary fibrosis: patterns and perpetrators
maxDepth	2
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Defective SFTPA2 causes IPF Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF)
normalPathway	[Pathway:R-HSA-5683826] Surfactant metabolism
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6791021] D'Eustachio, Peter, 2015-08-17
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5687868
summation	[Summation:5687975] One function of the pulmonary collectins, surfactant protein...
updateTrackers	[UpdateTracker:9778764] Update Tracker - [Pathway:5687868] Defective SFTPA2 causes IPF - v67:[updateContainedRLE]

(updatedInstance)	[UpdateTracker:9778764] Update Tracker - [Pathway:5687868] Defective SFTPA2 causes IPF - v67:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-5687613] Diseases associated with surfactant metabolism

Cite Us!