Reactome | FOXO3 regulates MIR34B,C expression

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:5685867] Rothfels, Karen, 2015-03-30
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5687104] Rothfels, Karen, 2015-04-06
dbId	5687103
displayName	FOXO3 regulates MIR34B,C expression
edited	[InstanceEdit:5692861] Rothfels, Karen, 2015-05-13
eventOf	[Pathway:R-HSA-5687128] MAPK6/MAPK4 signaling - Homo sapiens
input	[DefinedSet:R-HSA-5687040] MIR34B,C genes [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5686845] The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FOXO3 regulates MIR34B,C expression
output	[DefinedSet:R-HSA-5687043] miR-34B,C RISC [cytosol]
regulatedBy	[PositiveRegulation:R-HSA-5687137] Positive regulation by 'p-S215 FOXO3:MIR34B,C genes [nucleoplasm]'
releaseDate	2015-06-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5690232] Moens, Ugo, 2015-04-24 [InstanceEdit:5691290] Seternes, Ole-Morten, 2015-05-05 [InstanceEdit:5692746] Mathien, Simon, 2015-05-12 [InstanceEdit:5692748] Meloche, Sylvain, 2015-05-12 [InstanceEdit:5692747] Soulez, Mathilde, 2015-05-12
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-5687103
summation	[Summation:5686892] p-S215 FOXO3 binds to the promoter of the MIR34B and C gene ...

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