Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Complex
>
Entries
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]
Show undefined attributes
Go to Details
compartment
[Compartment:876] plasma membrane
created
[InstanceEdit:5675415] Rothfels, Karen, 2015-02-16
dbId
5675413
displayName
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]
hasComponent
[Complex:R-HSA-5675414] p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-61487] PEBP1 [cytosol]
inDisease
false
includedLocation
[Compartment:70101] cytosol
inferredTo
[Complex:R-MMU-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Mus musculus
[Complex:R-RNO-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Rattus norvegicus
[Complex:R-CFA-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Canis familiaris
[Complex:R-BTA-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Bos taurus
[Complex:R-SSC-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Sus scrofa
[Complex:R-DRE-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Danio rerio
[Complex:R-XTR-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Xenopus tropicalis
[Complex:R-GGA-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Gallus gallus
[Complex:R-DME-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Drosophila melanogaster
[Complex:R-CEL-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Caenorhabditis elegans
[Complex:R-DDI-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Dictyostelium discoideum
[Complex:R-PFA-5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - Plasmodium falciparum
isChimeric
false
maxDepth
5
name
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1
negativelyRegulates
[NegativeRegulation:R-HSA-8936739] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-8936736] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-8936742] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-8936741] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-8936734] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-5675436] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
producedByEvent
[Reaction:R-HSA-5675417] PEBP1 binds activated RAF1 - Homo sapiens
schemaClass
Complex
species
[Species:48887] Homo sapiens
stId
R-HSA-5675413
updateTrackers
[UpdateTracker:9900638] Update Tracker - [Complex:5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - v70:[updateContainedComponent]
Referrals
(updatedInstance)
[UpdateTracker:9900638] Update Tracker - [Complex:5675413] p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] - v70:[updateContainedComponent]
(regulator)
[NegativeRegulation:R-HSA-8936739] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-8936736] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-8936742] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-8936741] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-8936734] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
[NegativeRegulation:R-HSA-5675436] Negative regulation by 'p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane]'
(output)
[Reaction:R-HSA-5675417] PEBP1 binds activated RAF1
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text