Reactome | CIT [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-5671981] CIT:CDKN1B [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5671972] CIT binds CDKN1B - Homo sapiens [Reaction:R-HSA-5625901] CIT (citron kinase) binds activated RHOA, RHOB, RHOC and RAC1 - Homo sapiens
created	[InstanceEdit:5671922] Orlic-Milacic, Marija, 2015-02-03
dbId	5671920
displayName	CIT [cytosol]
hasComponent	2 × [EntityWithAccessionedSequence:R-HSA-1629806] CIT [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-5671920] CIT [cytosol] - Mus musculus [Complex:R-RNO-5671920] CIT [cytosol] - Rattus norvegicus [Complex:R-CFA-5671920] CIT [cytosol] - Canis familiaris [Complex:R-BTA-5671920] CIT [cytosol] - Bos taurus [Complex:R-SSC-5671920] CIT [cytosol] - Sus scrofa [Complex:R-GGA-5671920] CIT [cytosol] - Gallus gallus [Complex:R-DME-5671920] CIT [cytosol] - Drosophila melanogaster [Complex:R-CEL-5671920] CIT [cytosol] - Caenorhabditis elegans
isChimeric	false
literatureReference	[LiteratureReference:5625892] A novel partner for the GTP-bound forms of rho and rac
maxDepth	2
memberOf	[CandidateSet:R-HSA-9013003] RHOA plasma membrane effectors [cytosol] - Homo sapiens
name	CIT CIT dimer
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5671920

(hasMember)	[CandidateSet:R-HSA-9013003] RHOA plasma membrane effectors [cytosol]
(input)	[Reaction:R-HSA-5671972] CIT binds CDKN1B [Reaction:R-HSA-5625901] CIT (citron kinase) binds activated RHOA, RHOB, RHOC and RAC1
(hasComponent)	[Complex:R-HSA-5671981] CIT:CDKN1B [cytosol] [Complex:R-HSA-5625899] RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane]
(activeUnit)	[CatalystActivity:5671921] protein serine/threonine kinase activity of RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane]