Reactome | TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane]

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TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
consumedByEvent	[BlackBoxEvent:R-HSA-5668481] Protesomal degradation of K48polyUb-TRAF3 - Homo sapiens
created	[InstanceEdit:5668484] Garapati, Phani Vijay, 2015-01-26
dbId	5668442
displayName	TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane]
hasComponent	[Complex:R-HSA-5668450] K48polyUb-TRAF3:NIK [cytosol] [DefinedSet:R-HSA-5676550] TNFA:TNFR2,BAFF:BAFFR,TWEAK:Fn14,Lymphotoxin:LTBR,RANKL:RANK,CD40L:CD40 [plasma membrane] [Complex:R-HSA-5668475] TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - Mus musculus [Complex:R-RNO-5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - Rattus norvegicus [Complex:R-CFA-5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - Canis familiaris [Complex:R-BTA-5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - Bos taurus [Complex:R-SSC-5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - Sus scrofa [Complex:R-DRE-5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - Danio rerio [Complex:R-XTR-5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - Gallus gallus
isChimeric	false
maxDepth	8
modified	[InstanceEdit:5692520] Garapati, Phani Vijay, 2015-05-12
name	TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK
producedByEvent	[BlackBoxEvent:R-HSA-5668454] K63polyUb-cIAP1,2 ubiquitinates TRAF3 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5668442
updateTrackers	[UpdateTracker:9894197] Update Tracker - [Complex:5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - v57:[updateContainedComponent] [UpdateTracker:9904006] Update Tracker - [Complex:5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - v80:[updateContainedComponent] [UpdateTracker:9899936] Update Tracker - [Complex:5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - v67:[updateContainedComponent] [UpdateTracker:9897573] Update Tracker - [Complex:5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - v62:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9894197] Update Tracker - [Complex:5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - v57:[updateContainedComponent] [UpdateTracker:9904006] Update Tracker - [Complex:5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - v80:[updateContainedComponent] [UpdateTracker:9899936] Update Tracker - [Complex:5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - v67:[updateContainedComponent] [UpdateTracker:9897573] Update Tracker - [Complex:5668442] TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] - v62:[updateContainedComponent]
(input)	[BlackBoxEvent:R-HSA-5668481] Protesomal degradation of K48polyUb-TRAF3
(output)	[BlackBoxEvent:R-HSA-5668454] K63polyUb-cIAP1,2 ubiquitinates TRAF3

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