Reactome | MT3:4Zn2+:4Cu+ [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5662592] May, Bruce, 2015-01-12
dbId	5662563
displayName	MT3:4Zn2+:4Cu+ [cytosol]
hasComponent	[SimpleEntity:R-ALL-3299744] Cu1+ [cytosol] [EntityWithAccessionedSequence:R-HSA-5660396] MT3 [cytosol] 4 × [SimpleEntity:R-ALL-29426] Zn2+ [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-5662563] MT3:4Zn2+:4Cu+ [cytosol] - Mus musculus [Complex:R-RNO-5662563] MT3:4Zn2+:4Cu+ [cytosol] - Rattus norvegicus [Complex:R-CFA-5662563] MT3:4Zn2+:4Cu+ [cytosol] - Canis familiaris [Complex:R-BTA-5662563] MT3:4Zn2+:4Cu+ [cytosol] - Bos taurus [Complex:R-SSC-5662563] MT3:4Zn2+:4Cu+ [cytosol] - Sus scrofa [Complex:R-DRE-5662563] MT3:4Zn2+:4Cu+ [cytosol] - Danio rerio [Complex:R-GGA-5662563] MT3:4Zn2+:4Cu+ [cytosol] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:5662513] Metal swap between Zn7-metallothionein-3 and amyloid-beta-Cu protects against amyloid-beta toxicity [LiteratureReference:5662545] Redox silencing of copper in metal-linked neurodegenerative disorders: reaction of Zn7metallothionein-3 with Cu2+ ions [LiteratureReference:5662487] Redox labile site in a Zn4 cluster of Cu4,Zn4-metallothionein-3
maxDepth	2
name	MT3:4Zn2+:4Cu+
producedByEvent	[BlackBoxEvent:R-HSA-5662613] MT3 exchanges zinc for copper - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5662563

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