Reactome | UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]

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UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:5653763] ISG15 transferase activity of UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-5653754] UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA - Homo sapiens
created	[InstanceEdit:5653758] Orlic-Milacic, Marija, 2014-12-01
dbId	5653760
displayName	UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
hasComponent	[Complex:R-HSA-5653660] DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] [Complex:R-HSA-5653664] UBE2L6:TRIM25 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Mus musculus [Complex:R-RNO-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Canis familiaris [Complex:R-BTA-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Bos taurus [Complex:R-SSC-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Sus scrofa [Complex:R-DRE-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Danio rerio [Complex:R-XTR-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Gallus gallus [Complex:R-DME-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Caenorhabditis elegans [Complex:R-PFA-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Plasmodium falciparum
isChimeric	false
literatureReference	[LiteratureReference:5653648] Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis
maxDepth	7
modified	[InstanceEdit:5663021] Orlic-Milacic, Marija, 2015-01-14
name	UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template
producedByEvent	[Reaction:R-HSA-5653756] TRIM25 binds monoUb:164-PCNA - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5653760
updateTrackers	[UpdateTracker:9896939] Update Tracker - [Complex:5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - v61:[updateContainedComponent] [UpdateTracker:9894050] Update Tracker - [Complex:5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - v56:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9896939] Update Tracker - [Complex:5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - v61:[updateContainedComponent] [UpdateTracker:9894050] Update Tracker - [Complex:5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - v56:[updateContainedComponent]
(output)	[Reaction:R-HSA-5653756] TRIM25 binds monoUb:164-PCNA
(input)	[Reaction:R-HSA-5653754] UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA
(physicalEntity)	[CatalystActivity:5653763] ISG15 transferase activity of UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]

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