Reactome | APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm]

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APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:5651811] 5'-flap endonuclease activity of APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-110363] FEN1 bound to PCNA and APEX1 cleaves flap ssDNA - Homo sapiens
created	[InstanceEdit:5651806] Orlic-Milacic, Marija, 2014-11-24
dbId	5651812
displayName	APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-50119] APEX1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-54745] FEN1 [nucleoplasm] [Complex:R-HSA-5651799] PCNA:POLD,POLE:RPA:RFC [nucleoplasm] [GenomeEncodedEntity:R-HSA-5649865] SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Mus musculus [Complex:R-RNO-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Canis familiaris [Complex:R-BTA-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Bos taurus [Complex:R-SSC-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Sus scrofa [Complex:R-DRE-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Danio rerio [Complex:R-GGA-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Gallus gallus [Complex:R-DME-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Caenorhabditis elegans [Complex:R-SPO-5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - Schizosaccharomyces pombe
isChimeric	false
maxDepth	5
modified	[InstanceEdit:5651813] Orlic-Milacic, Marija, 2014-11-24
name	APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA
producedByEvent	[Reaction:R-HSA-110368] POLD,POLE-mediated DNA strand displacement synthesis - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5651812
updateTrackers	[UpdateTracker:9894414] Update Tracker - [Complex:5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - v57:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9894414] Update Tracker - [Complex:5651812] APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] - v57:[updateContainedComponent]
(input)	[Reaction:R-HSA-110363] FEN1 bound to PCNA and APEX1 cleaves flap ssDNA
(physicalEntity)	[CatalystActivity:5651811] 5'-flap endonuclease activity of APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm]
(output)	[Reaction:R-HSA-110368] POLD,POLE-mediated DNA strand displacement synthesis

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