Reactome | TNFSF10:TNFRSF10A,B Trimer [plasma membrane]

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TNFSF10:TNFRSF10A,B Trimer [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-75187] TRAIL:TRAIL receptor trimers bind FADD - Homo sapiens
created	[InstanceEdit:5637462] Orlic-Milacic, Marija, 2014-11-10
dbId	5637469
displayName	TNFSF10:TNFRSF10A,B Trimer [plasma membrane]
hasComponent	3 × [Complex:R-HSA-5637465] TNFSF10:TNFRSF10A,B [plasma membrane]
inDisease	false
includedLocation	[Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-5637469] TNFSF10:TNFRSF10A,B Trimer [plasma membrane] - Mus musculus [Complex:R-RNO-5637469] TNFSF10:TNFRSF10A,B Trimer [plasma membrane] - Rattus norvegicus [Complex:R-BTA-5637469] TNFSF10:TNFRSF10A,B Trimer [plasma membrane] - Bos taurus [Complex:R-SSC-5637469] TNFSF10:TNFRSF10A,B Trimer [plasma membrane] - Sus scrofa [Complex:R-DRE-5637469] TNFSF10:TNFRSF10A,B Trimer [plasma membrane] - Danio rerio [Complex:R-GGA-5637469] TNFSF10:TNFRSF10A,B Trimer [plasma membrane] - Gallus gallus
literatureReference	[LiteratureReference:141128] FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2 [LiteratureReference:3371348] Unraveling the binding mechanism of trivalent tumor necrosis factor ligands and their receptors
maxDepth	4
name	TNFSF10:TNFRSF10A,B Trimer TRAIL receptor-1,2:TRAIL Trimer
producedByEvent	[Reaction:R-HSA-141139] Trimerization of TRAIL:TRAIL receptor complex - Homo sapiens
revised	[InstanceEdit:5637455] Orlic-Milacic, Marija, 2014-11-10
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5637469

Referrals

(output)	[Reaction:R-HSA-141139] Trimerization of TRAIL:TRAIL receptor complex
(input)	[Reaction:R-HSA-75187] TRAIL:TRAIL receptor trimers bind FADD
(hasComponent)	[Complex:R-HSA-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane]

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