Reactome | Activated protein C:PROCR binds F2R

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Activated protein C:PROCR binds F2R Show undefined attributes

authored	[InstanceEdit:5607780] Jupe, Steve, 2014-07-14
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5607040] Jupe, Steve, 2014-07-09
dbId	5607058
displayName	Activated protein C:PROCR binds F2R
edited	[InstanceEdit:5627264] Jupe, Steve, 2014-07-28
eventOf	[Pathway:R-HSA-9769739] Regulation of clotting cascade - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-114531] Activated F2R [plasma membrane] [Complex:R-HSA-5603469] PROCR:Activated protein C [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5610094] Activation of endothelial cell protease activated receptor 1 by the protein C pathway
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Activated protein C:PROCR binds F2R
orthologousEvent	[Reaction:R-GGA-5607058] Activated protein C:PROCR binds F2R - Gallus gallus [Reaction:R-SSC-5607058] Activated protein C:PROCR binds F2R - Sus scrofa [Reaction:R-BTA-5607058] Activated protein C:PROCR binds F2R - Bos taurus [Reaction:R-CFA-5607058] Activated protein C:PROCR binds F2R - Canis familiaris [Reaction:R-RNO-5607058] Activated protein C:PROCR binds F2R - Rattus norvegicus [Reaction:R-MMU-5607058] Activated protein C:PROCR binds F2R - Mus musculus
output	[Complex:R-HSA-5607093] PROCR:Activated protein C:F2R [plasma membrane]
releaseDate	2014-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5627265] Mumford, Andrew, 2014-09-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5607058
summation	[Summation:5607052] F2R (PAR1) mediates multiple cytoprotective effects of Activ...
systematicName	PROCR:Activated protein C binds F2R
updateTrackers	[UpdateTracker:9846813] Update Tracker - [Reaction:5607058] Activated protein C:PROCR binds F2R - v84:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9846813] Update Tracker - [Reaction:5607058] Activated protein C:PROCR binds F2R - v84:[modifyText]
(hasEvent)	[Pathway:R-HSA-9769739] Regulation of clotting cascade

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