Reactome | Mitochondrial translation elongation

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Mitochondrial translation elongation Show undefined attributes

authored	[InstanceEdit:5368289] May, Bruce, 2014-04-26
compartment	[Compartment:5460] mitochondrial matrix [Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:5389835] May, Bruce, 2014-04-30
dbId	5389840
displayName	Mitochondrial translation elongation
edited	[InstanceEdit:5368289] May, Bruce, 2014-04-26
eventOf	[Pathway:R-HSA-5368287] Mitochondrial translation - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:383920] mitochondrial translational elongation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-5389845] TUFM:GTP binds aminoacyl-tRNA - Homo sapiens [Reaction:R-HSA-5389848] TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA - Homo sapiens [Reaction:R-HSA-5389842] TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome - Homo sapiens [Reaction:R-HSA-5389857] Peptide transfer from P-site to A-site (peptide bond formation) - Homo sapiens [Reaction:R-HSA-5419261] 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP - Homo sapiens [Reaction:R-HSA-5419279] Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) - Homo sapiens [Reaction:R-HSA-5419269] TSFM binds TUFM displacing GDP - Homo sapiens [Reaction:R-HSA-5419268] TUFM binds GTP displacing TSFM - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2016-03-24
literatureReference	[LiteratureReference:5423521] Mechanism of protein biosynthesis in mammalian mitochondria [LiteratureReference:5624378] Co-translational membrane insertion of mitochondrially encoded proteins [LiteratureReference:5432666] Structural aspects of mitochondrial translational apparatus
maxDepth	2
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Mitochondrial translation elongation
orthologousEvent	[Pathway:R-CFA-5389840] Mitochondrial translation elongation - Canis familiaris [Pathway:R-CEL-5389840] Mitochondrial translation elongation - Caenorhabditis elegans [Pathway:R-DME-5389840] Mitochondrial translation elongation - Drosophila melanogaster [Pathway:R-GGA-5389840] Mitochondrial translation elongation - Gallus gallus [Pathway:R-XTR-5389840] Mitochondrial translation elongation - Xenopus tropicalis [Pathway:R-DRE-5389840] Mitochondrial translation elongation - Danio rerio [Pathway:R-SSC-5389840] Mitochondrial translation elongation - Sus scrofa [Pathway:R-BTA-5389840] Mitochondrial translation elongation - Bos taurus [Pathway:R-RNO-5389840] Mitochondrial translation elongation - Rattus norvegicus [Pathway:R-MMU-5389840] Mitochondrial translation elongation - Mus musculus
releaseDate	2014-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5621503] Chrzanowska-Lightowlers, Zofia M A, 2014-08-29 [InstanceEdit:5624178] Spremulli, Linda L, 2014-09-20
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5389840
summation	[Summation:5487099] Translation elongation proceeds by cycles of aminoacyl-tRNAs...
updateTrackers	[UpdateTracker:9785606] Update Tracker - [Pathway:5389840] Mitochondrial translation elongation - v51:[addLiteratureReference, modifyText, updateContainedRLE] [UpdateTracker:9783483] Update Tracker - [Pathway:5389840] Mitochondrial translation elongation - v56:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9785606] Update Tracker - [Pathway:5389840] Mitochondrial translation elongation - v51:[addLiteratureReference, modifyText, updateContainedRLE] [UpdateTracker:9783483] Update Tracker - [Pathway:5389840] Mitochondrial translation elongation - v56:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-5368287] Mitochondrial translation

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