Reactome | CYGB binds O2

Schema > Reaction > Entries

CYGB binds O2 Show undefined attributes

authored	[InstanceEdit:5340205] Jassal, Bijay, 2014-03-12
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5340205] Jassal, Bijay, 2014-03-12
dbId	5340214
displayName	CYGB binds O2
edited	[InstanceEdit:5340205] Jassal, Bijay, 2014-03-12
eventOf	[Pathway:R-HSA-8981607] Intracellular oxygen transport - Homo sapiens
followingEvent	[Reaction:R-HSA-5340226] CYGB dioxygenates NO - Homo sapiens
input	[Complex:R-HSA-5340240] CYGB(Fe2+) dimer [cytosol] 2 × [SimpleEntity:R-ALL-29368] O2 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5340184] A ubiquitously expressed human hexacoordinate hemoglobin [LiteratureReference:5340202] The redox state of the cell regulates the ligand binding affinity of human neuroglobin and cytoglobin [LiteratureReference:5340215] Allosteric regulation and temperature dependence of oxygen binding in human neuroglobin and cytoglobin. Molecular mechanisms and physiological significance [LiteratureReference:9005931] Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	CYGB binds O2
orthologousEvent	[Reaction:R-CEL-5340214] CYGB binds O2 - Caenorhabditis elegans [Reaction:R-GGA-5340214] CYGB binds O2 - Gallus gallus [Reaction:R-XTR-5340214] CYGB binds O2 - Xenopus tropicalis [Reaction:R-DRE-5340214] CYGB binds O2 - Danio rerio [Reaction:R-SSC-5340214] CYGB binds O2 - Sus scrofa [Reaction:R-BTA-5340214] CYGB binds O2 - Bos taurus [Reaction:R-CFA-5340214] CYGB binds O2 - Canis familiaris [Reaction:R-RNO-5340214] CYGB binds O2 - Rattus norvegicus [Reaction:R-MMU-5340214] CYGB binds O2 - Mus musculus
output	[Complex:R-HSA-5340212] CYGB dimer:O2 [cytosol]
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005921] Burmester, Thorsten, 2017-05-11 [InstanceEdit:5674208] D'Eustachio, Peter, 2015-02-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5340214
summation	[Summation:5340213] Vertebrates possess multiple respiratory globins that differ...
updateTrackers	[UpdateTracker:9781501] Update Tracker - [Reaction:5340214] CYGB binds O2 - v61:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9781501] Update Tracker - [Reaction:5340214] CYGB binds O2 - v61:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-8981607] Intracellular oxygen transport
(precedingEvent)	[Reaction:R-HSA-5340226] CYGB dioxygenates NO
(reverseReaction)	[Reaction:R-HSA-8982617] CYGB:O2 dissociates