Reactome | pagA(197-794):ANTXR2 oligomer [plasma membrane]

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pagA(197-794):ANTXR2 oligomer [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5210937] cya:lef:(pagA(197-794):ANTXR2 oligomer) [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5210892] cya and lef bind to pagA(197-794):ANTXR2 oligomer - Homo sapiens
created	[InstanceEdit:5210902] D'Eustachio, Peter, 2013-12-07
crossReference	[DatabaseIdentifier:12020807] Mondo:0005119
dbId	5210895
disease	[Disease:5205706] anthrax disease
displayName	pagA(197-794):ANTXR2 oligomer [plasma membrane]
goCellularComponent	[GO_CellularComponent:6485] host cell plasma membrane
hasComponent	8 × [Complex:R-HSA-5210020] pagA(197-794):ANTXR2 [plasma membrane]
inDisease	true
isChimeric	false
literatureReference	[LiteratureReference:5487071] Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization in plasma [LiteratureReference:5487056] The protective antigen component of anthrax toxin forms functional octameric complexes
maxDepth	4
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	pagA(197-794):ANTXR2 oligomer PA63:ANTXR2 oligomer 8(PA63:ANTXR2)
producedByEvent	[Reaction:R-HSA-5210932] ANTXR2-bound pagA(197-794) forms oligomers - Homo sapiens
relatedSpecies	[Species:5205709] Bacillus anthracis
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5210895
updateTrackers	[UpdateTracker:9901724] Update Tracker - [Complex:5210895] pagA(197-794):ANTXR2 oligomer [plasma membrane] - v75:[addName, updateContainedComponent] [UpdateTracker:9895860] Update Tracker - [Complex:5210895] pagA(197-794):ANTXR2 oligomer [plasma membrane] - v60:[removeSpecies, updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9901724] Update Tracker - [Complex:5210895] pagA(197-794):ANTXR2 oligomer [plasma membrane] - v75:[addName, updateContainedComponent] [UpdateTracker:9895860] Update Tracker - [Complex:5210895] pagA(197-794):ANTXR2 oligomer [plasma membrane] - v60:[removeSpecies, updateContainedComponent]
(output)	[Reaction:R-HSA-5210932] ANTXR2-bound pagA(197-794) forms oligomers
(input)	[Reaction:R-HSA-5210892] cya and lef bind to pagA(197-794):ANTXR2 oligomer
(hasComponent)	[Complex:R-HSA-5210937] cya:lef:(pagA(197-794):ANTXR2 oligomer) [plasma membrane]

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