Reactome | p-STAT5 dimer [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9012668] CISH gene, SOCS1 gene, SOCS2 gene:p-STAT5 dimer [nucleoplasm] - Homo sapiens [Complex:R-HSA-9978235] p-STAT5 dimer:IL4R gene [nucleoplasm] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-9012671] p-STAT5 binds CISH, SOCS1 and SOCS2 gene - Homo sapiens [Reaction:R-HSA-9978250] Phosphorylated STAT5 dimer binds the IL4R gene - Homo sapiens [Reaction:R-HSA-8865626] p-STAT5 dimers bind the BRWD1 gene promoter - Homo sapiens
created	[InstanceEdit:508009] Jupe, S, 2010-02-10
dbId	508012
displayName	p-STAT5 dimer [nucleoplasm]
hasComponent	2 × [DefinedSet:R-HSA-1469978] p-STAT5 [nucleoplasm]
inDisease	false
maxDepth	3
memberOf	[DefinedSet:R-HSA-9674540] p-Y-STAT1,3,5 dimer [nucleoplasm] - Homo sapiens
modified	[InstanceEdit:2752148] May, B, 2012-12-08
name	p-STAT5 dimer
producedByEvent	[BlackBoxEvent:R-HSA-507937] STAT5 dimers translocate to the nucleus - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-508012

(input)	[BlackBoxEvent:R-HSA-9012671] p-STAT5 binds CISH, SOCS1 and SOCS2 gene [Reaction:R-HSA-9978250] Phosphorylated STAT5 dimer binds the IL4R gene [Reaction:R-HSA-8865626] p-STAT5 dimers bind the BRWD1 gene promoter
(hasComponent)	[Complex:R-HSA-9012668] CISH gene, SOCS1 gene, SOCS2 gene:p-STAT5 dimer [nucleoplasm] [Complex:R-HSA-9978235] p-STAT5 dimer:IL4R gene [nucleoplasm] [Complex:R-HSA-8865622] 2x(p-STAT5A,p-STAT5B):BRWD1 gene [nucleoplasm]
(activeUnit)	[PositiveRegulation:R-HSA-8983073] Positive regulation by 'CISH gene, SOCS1 gene, SOCS2 gene:p-STAT5 dimer [nucleoplasm]' [PositiveGeneExpressionRegulation:9978245] Positive gene expression regulation by 'p-STAT5 dimer:IL4R gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8865694] Negative gene expression regulation by '2x(p-STAT5A,p-STAT5B):BRWD1 gene [nucleoplasm]'
(hasMember)	[DefinedSet:R-HSA-9674540] p-Y-STAT1,3,5 dimer [nucleoplasm]
(output)	[BlackBoxEvent:R-HSA-507937] STAT5 dimers translocate to the nucleus