Reactome | Aquaporins passively transport glycerol out of cells

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Aquaporins passively transport glycerol out of cells Show undefined attributes

authored	[InstanceEdit:507886] May, B, 2010-02-09
catalystActivity	[CatalystActivity:507883] glycerol channel activity of AQP3,7,9,10 [plasma membrane]
catalystActivityReference	[CatalystActivityReference:9643845] glycerol channel activity of AQP3,7,9,10 [plasma membrane] Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:507878] May, B, 2010-02-09
crossReference	[DatabaseIdentifier:12668138] RHEA:29675
dbId	507871
displayName	Aquaporins passively transport glycerol out of cells
edited	[InstanceEdit:507886] May, B, 2010-02-09
eventOf	[Pathway:R-HSA-432047] Passive transport by Aquaporins - Homo sapiens
input	[SimpleEntity:R-ALL-76116] Glycerol [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:431832] Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin [LiteratureReference:431837] Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum [LiteratureReference:431908] Functional and molecular characterization of the human neutral solute channel aquaporin-9 [LiteratureReference:431916] Functional characterization of human aquaporin 9 as a facilitative glycerol carrier [LiteratureReference:503960] Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability [LiteratureReference:504025] Functional characterization and localization of AQP3 in the human colon [LiteratureReference:431959] Mercury-sensitive residues and pore site in AQP3 water channel [LiteratureReference:503930] Roles of aquaporin-3 water channels in volume-regulatory water flow in a human epithelial cell line [LiteratureReference:431853] Compartmentalization of aquaporins in the human intestine [LiteratureReference:431848] Comparison of messenger RNA distribution for 60 proteins in fat cells vs the nonfat cells of human omental adipose tissue [LiteratureReference:431860] Differential expression of aquaporin 7 in adipose tissue of lean and obese high fat consumers [LiteratureReference:503956] Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation [LiteratureReference:431678] Altered aquaporin 9 expression and localization in human hepatocellular carcinoma [LiteratureReference:431939] Immunolocalization of AQP9 in liver, epididymis, testis, spleen, and brain
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Aquaporins passively transport glycerol out of cells
orthologousEvent	[Reaction:R-PFA-507871] Aquaporins passively transport glycerol out of cells - Plasmodium falciparum [Reaction:R-SCE-507871] Aquaporins passively transport glycerol out of cells - Saccharomyces cerevisiae [Reaction:R-SPO-507871] Aquaporins passively transport glycerol out of cells - Schizosaccharomyces pombe [Reaction:R-CEL-507871] Aquaporins passively transport glycerol out of cells - Caenorhabditis elegans [Reaction:R-GGA-507871] Aquaporins passively transport glycerol out of cells - Gallus gallus [Reaction:R-XTR-507871] Aquaporins passively transport glycerol out of cells - Xenopus tropicalis [Reaction:R-DRE-507871] Aquaporins passively transport glycerol out of cells - Danio rerio [Reaction:R-SSC-507871] Aquaporins passively transport glycerol out of cells - Sus scrofa [Reaction:R-BTA-507871] Aquaporins passively transport glycerol out of cells - Bos taurus [Reaction:R-CFA-507871] Aquaporins passively transport glycerol out of cells - Canis familiaris [Reaction:R-RNO-507871] Aquaporins passively transport glycerol out of cells - Rattus norvegicus [Reaction:R-MMU-507871] Aquaporins passively transport glycerol out of cells - Mus musculus
output	[SimpleEntity:R-ALL-192438] glycerol [extracellular region]
releaseDate	2009-06-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:879857] Beitz, E, 2010-06-24 [InstanceEdit:913479] Calamita, G, 2010-07-15 [InstanceEdit:918100] Mathai, JC, MacIver, B, 2010-07-31
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-507871
summation	[Summation:507872] Aquaporin-3 (AQP3), AQP7, AQP9, and AQP10 are 6-pass transme...

Referrals

(hasEvent)	[Pathway:R-HSA-432047] Passive transport by Aquaporins
(reverseReaction)	[Reaction:R-HSA-507869] Aquaporins passively transport glycerol into cells

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