Reactome | truncated AMER1 mutants [cytosol]

Schema > CandidateSet > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[FailedReaction:R-HSA-4839746] Truncated AMER1 mutants destabilize the destruction complex - Homo sapiens
created	[InstanceEdit:4839740] Rothfels, K, 2013-11-02
crossReference	[DatabaseIdentifier:12020838] Mondo:0019004
dbId	4839741
disease	[Disease:1500689] cancer [Disease:4839624] nephroblastoma
displayName	truncated AMER1 mutants [cytosol]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-4839640] AMER1 R358* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-5251492] AMER1 S210* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9663939] AMER1 R353* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9663943] AMER1 R497* [cytosol] - Homo sapiens
inDisease	true
maxDepth	2
modified	[InstanceEdit:9663945] Rothfels, Karen, 2019-10-18
name	truncated AMER1 mutants
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-4839741
updateTrackers	[UpdateTracker:9900924] Update Tracker - [CandidateSet:4839741] truncated AMER1 mutants [cytosol] - v71:[addHasCandidate]

(updatedInstance)	[UpdateTracker:9900924] Update Tracker - [CandidateSet:4839741] truncated AMER1 mutants [cytosol] - v71:[addHasCandidate]
(input)	[FailedReaction:R-HSA-4839746] Truncated AMER1 mutants destabilize the destruction complex
(diseaseEntity)	[EntityFunctionalStatus:4839739] loss_of_function of truncated AMER1 mutants [cytosol]