Reactome | TXLNA (IL14) binds syntaxin1A

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TXLNA (IL14) binds syntaxin1A Show undefined attributes

authored	[InstanceEdit:5578882] Jupe, Steve, 2014-06-04
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:449109] Jupe, S, 2009-11-27
dbId	449117
displayName	TXLNA (IL14) binds syntaxin1A
edited	[InstanceEdit:8854731] Jupe, Steve, 2016-01-28
eventOf	[Pathway:R-HSA-449836] Other interleukin signaling - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-449128] STX1A [plasma membrane] [EntityWithAccessionedSequence:R-HSA-449124] TXLNA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:449130] Taxilin; a novel syntaxin-binding protein that is involved in Ca2+-dependent exocytosis in neuroendocrine cells
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	TXLNA (IL14) binds syntaxin1A
orthologousEvent	[Reaction:R-CFA-449117] TXLNA (IL14) binds syntaxin1A - Canis familiaris [Reaction:R-DDI-449117] TXLNA (IL14) binds syntaxin1A - Dictyostelium discoideum [Reaction:R-CEL-449117] TXLNA (IL14) binds syntaxin1A - Caenorhabditis elegans [Reaction:R-DME-449117] TXLNA (IL14) binds syntaxin1A - Drosophila melanogaster [Reaction:R-GGA-449117] TXLNA (IL14) binds syntaxin1A - Gallus gallus [Reaction:R-SSC-449117] TXLNA (IL14) binds syntaxin1A - Sus scrofa [Reaction:R-BTA-449117] TXLNA (IL14) binds syntaxin1A - Bos taurus [Reaction:R-RNO-449117] TXLNA (IL14) binds syntaxin1A - Rattus norvegicus [Reaction:R-MMU-449117] TXLNA (IL14) binds syntaxin1A - Mus musculus
output	[Complex:R-HSA-449116] TXLNA:STX1A [plasma membrane]
regulatedBy	[NegativeRegulation:R-HSA-9014076] Negative regulation by 'STXA1:SNAP25,STXBP2, VAMP2 [plasma membrane]'
regulationReference	[RegulationReference:9642078] Negative regulation by 'STXA1:SNAP25,STXBP2, VAMP2 [plasma membrane]' Interaction of taxilin with syntaxin which does not form the SNARE complex
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8854753] Meldal, Birgit, 2016-01-28
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-449117
summation	[Summation:449137] Interleukin-14, renamed alpha-taxilin (TXLNA) was originally...
updateTrackers	[UpdateTracker:9780742] Update Tracker - [Reaction:449117] TXLNA (IL14) binds syntaxin1A - v62:[addRegulator, add_removeInput, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9780742] Update Tracker - [Reaction:449117] TXLNA (IL14) binds syntaxin1A - v62:[addRegulator, add_removeInput, modifyText]
(hasEvent)	[Pathway:R-HSA-449836] Other interleukin signaling