Reactome | SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol

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SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol Show undefined attributes

authored	[InstanceEdit:427553] Jassal, Bijay, 2009-06-23
catalystActivity	[CatalystActivity:427647] sodium:phosphate symporter activity of Type III Na+/Pi cotransporters [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:427553] Jassal, Bijay, 2009-06-23
crossReference	[DatabaseIdentifier:12668156] RHEA:71259 [DatabaseIdentifier:9959397] RHEA:71260
dbId	427605
diseaseReaction	[FailedReaction:R-HSA-5625123] Defective SLC20A2 does not cotransport Pi, Na+ from extracellular region to cytosol - Homo sapiens
displayName	SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol
edited	[InstanceEdit:427553] Jassal, Bijay, 2009-06-23
eventOf	[Pathway:R-HSA-427652] Sodium-coupled phosphate cotransporters - Homo sapiens
input	2 × [SimpleEntity:R-ALL-74113] Na+ [extracellular region] [SimpleEntity:R-ALL-109277] Pi [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:427627] Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus [LiteratureReference:427658] A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family [LiteratureReference:427597] NaPO(4) cotransport type III (PiT1) expression in human embryonic kidney cells and regulation by PTH
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol Type III Na+/Pi cotransport
orthologousEvent	[Reaction:R-PFA-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Plasmodium falciparum [Reaction:R-SCE-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Saccharomyces cerevisiae [Reaction:R-CEL-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Caenorhabditis elegans [Reaction:R-DME-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-GGA-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Gallus gallus [Reaction:R-XTR-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Xenopus tropicalis [Reaction:R-DRE-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Danio rerio [Reaction:R-SSC-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Sus scrofa [Reaction:R-BTA-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Bos taurus [Reaction:R-CFA-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Canis familiaris [Reaction:R-RNO-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-MMU-427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - Mus musculus
output	2 × [SimpleEntity:R-ALL-83910] Na+ [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:433651] He, L, 2009-08-24
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-427605
summation	[Summation:427639] There are two transporters of this type; The genes SLC20A1 a...
updateTrackers	[UpdateTracker:9785774] Update Tracker - [Reaction:427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - v51:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9785774] Update Tracker - [Reaction:427605] SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol - v51:[modifyText]
(normalReaction)	[FailedReaction:R-HSA-5625123] Defective SLC20A2 does not cotransport Pi, Na+ from extracellular region to cytosol
(hasEvent)	[Pathway:R-HSA-427652] Sodium-coupled phosphate cotransporters

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