Reactome | SLC9A9 exchanges Na+ for H+ across the late endosome membrane

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SLC9A9 exchanges Na+ for H+ across the late endosome membrane Show undefined attributes

authored	[InstanceEdit:425976] Jassal, Bijay, 2009-06-11
catalystActivity	[CatalystActivity:426009] sodium:proton antiporter activity of SLC9A9 [late endosome membrane]
category	transition
compartment	[Compartment:172574] late endosome membrane
created	[InstanceEdit:425976] Jassal, Bijay, 2009-06-11
crossReference	[DatabaseIdentifier:12668188] RHEA:29419 [DatabaseIdentifier:9958514] RHEA:29421
dbId	425965
diseaseReaction	[FailedReaction:R-HSA-5661086] Defective SLC9A9 does not exchange Na+ for H+ across the late endosome membrane - Homo sapiens
displayName	SLC9A9 exchanges Na+ for H+ across the late endosome membrane
edited	[InstanceEdit:425976] Jassal, Bijay, 2009-06-11
eventOf	[Pathway:R-HSA-425986] Sodium/Proton exchangers - Homo sapiens
input	[SimpleEntity:R-ALL-425999] H+ [late endosome lumen] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:425970] Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	SLC9A9 exchanges Na+ for H+ across the late endosome membrane Na+/H+ exchanger transport (at late endosome membrane)
orthologousEvent	[Reaction:R-SCE-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Saccharomyces cerevisiae [Reaction:R-SPO-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Schizosaccharomyces pombe [Reaction:R-DDI-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Dictyostelium discoideum [Reaction:R-CEL-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Caenorhabditis elegans [Reaction:R-DME-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Drosophila melanogaster [Reaction:R-GGA-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Gallus gallus [Reaction:R-XTR-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Xenopus tropicalis [Reaction:R-SSC-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Sus scrofa [Reaction:R-BTA-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Bos taurus [Reaction:R-CFA-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Canis familiaris [Reaction:R-RNO-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Rattus norvegicus [Reaction:R-MMU-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Mus musculus
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-425977] Na+ [late endosome lumen]
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:433651] He, L, 2009-08-24
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-425965
summation	[Summation:426013] NHE9 (SLC9A9) (Nakamura al. 2005) is expressed ubiquitously ...
updateTrackers	[UpdateTracker:9785216] Update Tracker - [Reaction:425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - v52:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9785216] Update Tracker - [Reaction:425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - v52:[modifyText]
(normalReaction)	[FailedReaction:R-HSA-5661086] Defective SLC9A9 does not exchange Na+ for H+ across the late endosome membrane
(hasEvent)	[Pathway:R-HSA-425986] Sodium/Proton exchangers