Reactome | Polysialylation of NCAM1

Schema > Reaction > Entries

Polysialylation of NCAM1 Show undefined attributes

authored	[InstanceEdit:422456] Garapati, P V, 2009-05-30 17:44:08
catalystActivity	[CatalystActivity:422455] alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity of alpha 2-8 polysialyltransferases [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:422456] Garapati, P V, 2009-05-30 17:44:08
dbId	422454
displayName	Polysialylation of NCAM1
edited	[InstanceEdit:422456] Garapati, P V, 2009-05-30 17:44:08
eventOf	[Pathway:R-HSA-419037] NCAM1 interactions - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-422430] 6xN-linked glycan core-NCAM1 [Golgi membrane] 2 × [Polymer:R-HSA-422427] Polysialic acid [Golgi membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:422446] Polysialic acid in the plasticity of the developing and adult vertebrate nervous system [LiteratureReference:422420] Polysialyltransferases: major players in polysialic acid synthesis on the neural cell adhesion molecule [LiteratureReference:422442] Genetic ablation of polysialic acid causes severe neurodevelopmental defects rescued by deletion of the neural cell adhesion molecule
maxDepth	1
modified	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
name	Polysialylation of NCAM1
orthologousEvent	[Reaction:R-CFA-422454] Polysialylation of NCAM1 - Canis familiaris [Reaction:R-RNO-422454] Polysialylation of NCAM1 - Rattus norvegicus [Reaction:R-MMU-422454] Polysialylation of NCAM1 - Mus musculus
output	[Complex:R-HSA-422441] Polysialylated NCAM [Golgi membrane]
releaseDate	2009-06-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:422107] Maness, PF, Walmod, PS, 2009-05-25
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-422454
summation	[Summation:422419] NCAM in the developing brain is highly polysialylated and is...
updateTrackers	[UpdateTracker:9791474] Update Tracker - [Reaction:422454] Polysialylation of NCAM1 - v30:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9791474] Update Tracker - [Reaction:422454] Polysialylation of NCAM1 - v30:[modifyText]
(hasEvent)	[Pathway:R-HSA-419037] NCAM1 interactions