Reactome | HDAC3 containing complexes deacetylate histone

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HDAC3 containing complexes deacetylate histone Show undefined attributes

authored	[InstanceEdit:3214866] Jupe, S, 2013-03-12
catalystActivity	[CatalystActivity:4663845] histone deacetylase activity of HDAC3-containing complex [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3777161] Jupe, S, 2013-06-26
dbId	3777129
displayName	HDAC3 containing complexes deacetylate histone
edited	[InstanceEdit:3214866] Jupe, S, 2013-03-12
eventOf	[Pathway:R-HSA-3214815] HDACs deacetylate histones - Homo sapiens
input	[Complex:R-HSA-4663858] Acetylated core histone octamer [nucleoplasm] [SimpleEntity:R-ALL-113518] H2O [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3772090] The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	HDAC3 containing complexes deacetylate histone
orthologousEvent	[Reaction:R-XTR-3777129] HDAC3 containing complexes deacetylate histone - Xenopus tropicalis [Reaction:R-BTA-3777129] HDAC3 containing complexes deacetylate histone - Bos taurus [Reaction:R-RNO-3777129] HDAC3 containing complexes deacetylate histone - Rattus norvegicus
output	[SimpleEntity:R-ALL-5566518] acetate [nucleoplasm] [Complex:R-HSA-4657034] Core histone octamer [nucleoplasm]
releaseDate	2014-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5423007] Yang, Xiang-Jiao, 2014-05-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-3777129
summation	[Summation:3777170] HDAC3 mediates the gene silencing activity of Retinoic acid ...

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(hasEvent)

[Pathway:R-HSA-3214815] HDACs deacetylate histones

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