Reactome | p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane]

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p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-372652] CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-372697] Crk binding to p130cas - Homo sapiens
created	[InstanceEdit:372649] Garapati, P V, 2008-06-27 10:19:06
dbId	372646
displayName	p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-372645] p-Y-BCAR1 [cytosol] [Complex:R-HSA-354080] Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - Mus musculus [Complex:R-RNO-372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - Canis familiaris [Complex:R-BTA-372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - Bos taurus [Complex:R-SSC-372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - Sus scrofa [Complex:R-GGA-372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - Gallus gallus
maxDepth	8
modified	[InstanceEdit:9634754] Rothfels, Karen, 2019-01-14
name	p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 Phosphorylated p130Cas in complex with FADK1 Phosphorylated p130Cas in complex with PTK2
producedByEvent	[Reaction:R-HSA-372693] Phosphorylation of BCAR1 by SRC-PTK2 complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-372646
updateTrackers	[UpdateTracker:9877265] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v44:[addName, updateContainedComponent] [UpdateTracker:9872368] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v41:[updateContainedComponent] [UpdateTracker:9928589] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v91:[updateContainedComponent] [UpdateTracker:9898782] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v64:[updateContainedComponent] [UpdateTracker:9869589] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v34:[modifyName, updateContainedComponent] [UpdateTracker:9867982] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v28:[updateContainedComponent] [UpdateTracker:9900124] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v68:[addName, updateContainedComponent] [UpdateTracker:9888309] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v46:[updateContainedComponent] [UpdateTracker:9894821] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v58:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9877265] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v44:[addName, updateContainedComponent] [UpdateTracker:9872368] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v41:[updateContainedComponent] [UpdateTracker:9928589] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v91:[updateContainedComponent] [UpdateTracker:9898782] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v64:[updateContainedComponent] [UpdateTracker:9869589] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v34:[modifyName, updateContainedComponent] [UpdateTracker:9867982] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v28:[updateContainedComponent] [UpdateTracker:9900124] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v68:[addName, updateContainedComponent] [UpdateTracker:9888309] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v46:[updateContainedComponent] [UpdateTracker:9894821] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v58:[updateContainedComponent]
(hasComponent)	[Complex:R-HSA-372652] CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane]
(input)	[Reaction:R-HSA-372697] Crk binding to p130cas
(output)	[Reaction:R-HSA-372693] Phosphorylation of BCAR1 by SRC-PTK2 complex

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